The invention relates to powder particles comprising a pharmaceutically acceptable salt of 8-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]-2(1H)-quinolinone (carmoterol) having improved adhesion properties for dry powder formulations for inhalation. The invention also relates to methods for preparing them, corresponding formulations in the form of powders for inhalation and uses thereof.
Microparticles comprising a salt of 8-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]-2(1H)-quinolinone having improved adhesion properties for dry powder inhalation / Buttini, Francesca; Cocconi, Daniela; Colombo, Paolo; Musa, Rossella; Parlati, Chiara. - (2010).
Microparticles comprising a salt of 8-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]-2(1H)-quinolinone having improved adhesion properties for dry powder inhalation
BUTTINI, Francesca;COCCONI, Daniela;COLOMBO, Paolo;PARLATI, Chiara
2010-01-01
Abstract
The invention relates to powder particles comprising a pharmaceutically acceptable salt of 8-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]-2(1H)-quinolinone (carmoterol) having improved adhesion properties for dry powder formulations for inhalation. The invention also relates to methods for preparing them, corresponding formulations in the form of powders for inhalation and uses thereof.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
