Gangliosides are biological glycolipids participating in rafts, structural and functional domains of cell membranes. Their headgroups are able to assume different conformations when packed on the surface of an aggregate, more lying or standing. Switching between different conformations is possible, and is a collective event. Switching can be induced, in model systems, by concentration or temperature increase, then possibly involving ganglioside-water interaction. In the present paper, the effect of GM1 ganglioside headgroup conformation on the water structuring and interactions is addressed.
Water response to ganglioside GM1 surface remodelling / Brocca, P; Rondelli, V; Mallamace, F; DI BARI, Maria; Deriu, Antonio; Lohstroh, W; Del Favero, E; Corti, M; Cantu', L.. - In: BIOCHIMICA ET BIOPHYSICA ACTA. - ISSN 0006-3002. - (2016). [10.1016/j.bbagen.2016.04.029]
Water response to ganglioside GM1 surface remodelling
DI BARI, Maria;DERIU, Antonio;
2016-01-01
Abstract
Gangliosides are biological glycolipids participating in rafts, structural and functional domains of cell membranes. Their headgroups are able to assume different conformations when packed on the surface of an aggregate, more lying or standing. Switching between different conformations is possible, and is a collective event. Switching can be induced, in model systems, by concentration or temperature increase, then possibly involving ganglioside-water interaction. In the present paper, the effect of GM1 ganglioside headgroup conformation on the water structuring and interactions is addressed.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
