The invention relates to the use of derivatives of 1-(2-fluorobiphenyl-4- yl)-alkyl carboxylic acid as agents capable of stabilising the tetrameric native state of transthyretin for the prophylaxis and treatment of amyloidosis.
“Derivatives of 1-(2-fluorobiphenyl-4-yl)-alkyl carboxylic acid for the therapy of transthyretin amyloidosis” / Imbimbo, Bruno Pietro; Villetti, Gino; Berni, Rodolfo. - (2014).
“Derivatives of 1-(2-fluorobiphenyl-4-yl)-alkyl carboxylic acid for the therapy of transthyretin amyloidosis”.
BERNI, Rodolfo
2014-01-01
Abstract
The invention relates to the use of derivatives of 1-(2-fluorobiphenyl-4- yl)-alkyl carboxylic acid as agents capable of stabilising the tetrameric native state of transthyretin for the prophylaxis and treatment of amyloidosis.File in questo prodotto:
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