MMVD is the most common acquired cardiovascular disease in dogs and it represents a natural model for human mitral valve disease; for these reasons it is a common research subject. MMVD has a benign progression with a long asymptomatic phase. The exact mechanism of neurohormonal activation, which lead to cardiac remodeling, is not completely clearified. Recently the role of serotonin in myxomatous degenerations has been demonstrated. Surgical valvular repair or mitral valve replacement gave encouraging results and it may represent a new therapeutical option. The three-dimensional echocardiography is a useful tool for mitral morpho-functional reasearch and it may be crucial for surgical treatment.
La malattia valvolare mitralica nel cane / Crosara, Serena; Borgarelli, Michele. - In: VETERINARIA. - ISSN 0394-3151. - 2:Aprile(2015), pp. 31-37.
La malattia valvolare mitralica nel cane
CROSARA, Serena;
2015-01-01
Abstract
MMVD is the most common acquired cardiovascular disease in dogs and it represents a natural model for human mitral valve disease; for these reasons it is a common research subject. MMVD has a benign progression with a long asymptomatic phase. The exact mechanism of neurohormonal activation, which lead to cardiac remodeling, is not completely clearified. Recently the role of serotonin in myxomatous degenerations has been demonstrated. Surgical valvular repair or mitral valve replacement gave encouraging results and it may represent a new therapeutical option. The three-dimensional echocardiography is a useful tool for mitral morpho-functional reasearch and it may be crucial for surgical treatment.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
