There are several guidelines addressing the issues around the use of NSAIDs. However, none has specifically addressed the upper versus lower gastrointestinal (GI) risk of COX-2 selective and non-selective compounds nor the interaction at both the GI and cardiovascular (CV) level of either class of drugs with low-dose aspirin. This Consensus paper aims to develop statements and guidance devoted to these specific issues through a review of current evidence by a multidisciplinary group of experts.

Safe prescribing of non-steroidal anti-inflammatory drugs in patients with osteoarthritis--an expert consensus addressing benefits as well as gastrointestinal and cardiovascular risks / Scarpignato, Carmelo; Lanas, Angel; Blandizzi, Corrado; Lems, Willem F; Hermann, Matthias; Hunt, Richard H.. - In: BMC MEDICINE. - ISSN 1741-7015. - 13:(2015), p. 55. [10.1186/s12916-015-0285-8]

Safe prescribing of non-steroidal anti-inflammatory drugs in patients with osteoarthritis--an expert consensus addressing benefits as well as gastrointestinal and cardiovascular risks

SCARPIGNATO, Carmelo;
2015-01-01

Abstract

There are several guidelines addressing the issues around the use of NSAIDs. However, none has specifically addressed the upper versus lower gastrointestinal (GI) risk of COX-2 selective and non-selective compounds nor the interaction at both the GI and cardiovascular (CV) level of either class of drugs with low-dose aspirin. This Consensus paper aims to develop statements and guidance devoted to these specific issues through a review of current evidence by a multidisciplinary group of experts.
2015
Safe prescribing of non-steroidal anti-inflammatory drugs in patients with osteoarthritis--an expert consensus addressing benefits as well as gastrointestinal and cardiovascular risks / Scarpignato, Carmelo; Lanas, Angel; Blandizzi, Corrado; Lems, Willem F; Hermann, Matthias; Hunt, Richard H.. - In: BMC MEDICINE. - ISSN 1741-7015. - 13:(2015), p. 55. [10.1186/s12916-015-0285-8]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2808692
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