The selection of populations to be screened for lung cancer must be further optimized before translation to large population. A 3-step refinement should be integrated into forthcoming lung cancer trials, namely, calculation of risk based on (1) demographics, (2) biological factors, and (3) radiologic inputs. Biological sampling should be implemented up-front to reduce the use of low-dose computed tomography scanning in patients with lower risk of aggressive disease and, notably, to improve detection of aggressive disease that is overlooked by current screening strategies.
Refining Strategies to Identify Populations to Be Screened for Lung Cancer / Pastorino, Ugo; Silva, Mario. - In: THORACIC SURGERY CLINICS. - ISSN 1547-4127. - 25:2(2015), pp. 217-221. [10.1016/j.thorsurg.2014.11.005]
Refining Strategies to Identify Populations to Be Screened for Lung Cancer
SILVA, Mario
2015-01-01
Abstract
The selection of populations to be screened for lung cancer must be further optimized before translation to large population. A 3-step refinement should be integrated into forthcoming lung cancer trials, namely, calculation of risk based on (1) demographics, (2) biological factors, and (3) radiologic inputs. Biological sampling should be implemented up-front to reduce the use of low-dose computed tomography scanning in patients with lower risk of aggressive disease and, notably, to improve detection of aggressive disease that is overlooked by current screening strategies.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
