The potential use of stem cells (SCs) for tissue engineering, regenerative medicine, disease modeling, toxicological studies, drug delivery, and as in vitro model for the study of basic developmental processes implies large-scale in vitro culture. Here, after a brief description of the main techniques used for karyotype analysis, we will give a detailed overview of the chromosome abnormalities described in pluripotent (embryonic and induced pluripotent SCs) and somatic SCs, and the possible causes of their origin during culture.

Chromosomal Abnormalities in Embryonic and Somatic Stem Cells / Rebuzzini, P; Zuccotti, Maurizio; Redi, Ca; Garagna, S.. - In: CYTOGENETIC AND GENOME RESEARCH. - ISSN 1424-8581. - 147:1(2015), pp. 1-9. [10.1159/000441645]

Chromosomal Abnormalities in Embryonic and Somatic Stem Cells

ZUCCOTTI, Maurizio;
2015-01-01

Abstract

The potential use of stem cells (SCs) for tissue engineering, regenerative medicine, disease modeling, toxicological studies, drug delivery, and as in vitro model for the study of basic developmental processes implies large-scale in vitro culture. Here, after a brief description of the main techniques used for karyotype analysis, we will give a detailed overview of the chromosome abnormalities described in pluripotent (embryonic and induced pluripotent SCs) and somatic SCs, and the possible causes of their origin during culture.
2015
Chromosomal Abnormalities in Embryonic and Somatic Stem Cells / Rebuzzini, P; Zuccotti, Maurizio; Redi, Ca; Garagna, S.. - In: CYTOGENETIC AND GENOME RESEARCH. - ISSN 1424-8581. - 147:1(2015), pp. 1-9. [10.1159/000441645]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2807905
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