Cancer cells, even in the presence of available oxygen, have a glycolysis enhancement. The "aerobic glycolysis" is known as the Warburg effect and it is considered one of the fundamental hallmarks of metabolic alteration during malignant transformation. A feature of many tumors is also a change into ions equilibrium, with particular reference to K(+) intracellular concentration. Another hallmark in cancer is the reprogrammed chemotaxis pathways in favour of tumor cell dissemination.
K-D:rib dampens Hs 578T cancer cell chemoinvasion and proliferation / Bruni, Luca; Babarinde, Adesola A; Ortalli, Ida; Croci, Simonetta. - In: CANCER CELL INTERNATIONAL. - ISSN 1475-2867. - 14:1(2014), pp. 77-84. [10.1186/s12935-014-0077-9]
K-D:rib dampens Hs 578T cancer cell chemoinvasion and proliferation
BRUNI, LUCA;ORTALLI, Ida;CROCI, Simonetta
2014-01-01
Abstract
Cancer cells, even in the presence of available oxygen, have a glycolysis enhancement. The "aerobic glycolysis" is known as the Warburg effect and it is considered one of the fundamental hallmarks of metabolic alteration during malignant transformation. A feature of many tumors is also a change into ions equilibrium, with particular reference to K(+) intracellular concentration. Another hallmark in cancer is the reprogrammed chemotaxis pathways in favour of tumor cell dissemination.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
