Calix[4]arenes derivatives 1 and 2, featuring two guanidine units at the upper rim, catalyze the transesterification of diribonucleoside monophosphates much more effectively than that of HPNP. Rate accelerations relative to the background range from 103 to 104-fold, and approach 105-fold with the most favorable substrate-catalyst combinations.
Diguanidinocalix[4]arenes as effective and selective catalysts of the cleavage of diribonucleoside monophosphates / Salvio, Riccardo; Cacciapaglia, Roberta; Mandolini, Luigi; Sansone, Francesco; Casnati, Alessandro. - In: RSC ADVANCES. - ISSN 2046-2069. - 4:65(2014), pp. 34412-34416. [10.1039/C4RA05751A]
Diguanidinocalix[4]arenes as effective and selective catalysts of the cleavage of diribonucleoside monophosphates
SANSONE, Francesco;CASNATI, Alessandro
2014-01-01
Abstract
Calix[4]arenes derivatives 1 and 2, featuring two guanidine units at the upper rim, catalyze the transesterification of diribonucleoside monophosphates much more effectively than that of HPNP. Rate accelerations relative to the background range from 103 to 104-fold, and approach 105-fold with the most favorable substrate-catalyst combinations.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
