A cross sectional case (241 males occupationally exposed to lead)-control (102 males unexposed to lead) study was performed with the aim of evaluating the relationship between serum prolactin (S-PRL) and lead blood (PbB) levels. A meta-analysis of S-PRL levels in similar studies was also carried out. No difference of S-PRL between groups or any relationship between PbB and S-PRL levels was found. The meta-analysis showed a slight increase of S-PRL levels among exposed people, the weighted means falling within the reference values of the biomarker. The results do not support a routine use of S-PRL as a biomarker of effect in lead exposed workers.

Lack of correlation between blood lead and serum prolactin levels among lead exposed workers / Catalani, Simona; DE PALMA, Giuseppe; Tomasi, Cesare; Alinovi, Rossella; Mutti, Antonio; Apostoli, Pietro. - In: BIOMARKERS. - ISSN 1354-750X. - 17:6(2012), pp. 513-519. [10.3109/1354750X.2012.692391]

Lack of correlation between blood lead and serum prolactin levels among lead exposed workers

DE PALMA, Giuseppe;ALINOVI, Rossella;MUTTI, Antonio;
2012-01-01

Abstract

A cross sectional case (241 males occupationally exposed to lead)-control (102 males unexposed to lead) study was performed with the aim of evaluating the relationship between serum prolactin (S-PRL) and lead blood (PbB) levels. A meta-analysis of S-PRL levels in similar studies was also carried out. No difference of S-PRL between groups or any relationship between PbB and S-PRL levels was found. The meta-analysis showed a slight increase of S-PRL levels among exposed people, the weighted means falling within the reference values of the biomarker. The results do not support a routine use of S-PRL as a biomarker of effect in lead exposed workers.
Lack of correlation between blood lead and serum prolactin levels among lead exposed workers / Catalani, Simona; DE PALMA, Giuseppe; Tomasi, Cesare; Alinovi, Rossella; Mutti, Antonio; Apostoli, Pietro. - In: BIOMARKERS. - ISSN 1354-750X. - 17:6(2012), pp. 513-519. [10.3109/1354750X.2012.692391]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2784177
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