Polymorphonuclear cells diapedesis has an important contribution to the induced Mannhemia haemolytica (M. haemolytica) infection lung inflammation and IL-8 is the primary polymorphonuclear chemoattractant. Using a bovine IL-8/luciferase transiently transgenized mouse model, the orchestration among M. haemolytica, IL-8 promoter activation and neutrophilia was followed in real time by in vivo image analysis.

Enlightened Mannhemia haemolytica lung inflammation in bovinized mice / Fabio, Stellari; Sophia, Lavrentiadou; Ruscitti, Francesca; Jacca, Sarah; Franceschi, Valentina; Maurizio, Civelli; Chiara, Carnini; Gino, Villetti; Donofrio, Gaetano. - In: VETERINARY RESEARCH. - ISSN 0928-4249. - 45:(2014), p. 8. [10.1186/1297-9716-45-8]

Enlightened Mannhemia haemolytica lung inflammation in bovinized mice

RUSCITTI, Francesca;JACCA, Sarah;FRANCESCHI, Valentina;DONOFRIO, Gaetano
2014-01-01

Abstract

Polymorphonuclear cells diapedesis has an important contribution to the induced Mannhemia haemolytica (M. haemolytica) infection lung inflammation and IL-8 is the primary polymorphonuclear chemoattractant. Using a bovine IL-8/luciferase transiently transgenized mouse model, the orchestration among M. haemolytica, IL-8 promoter activation and neutrophilia was followed in real time by in vivo image analysis.
2014
Enlightened Mannhemia haemolytica lung inflammation in bovinized mice / Fabio, Stellari; Sophia, Lavrentiadou; Ruscitti, Francesca; Jacca, Sarah; Franceschi, Valentina; Maurizio, Civelli; Chiara, Carnini; Gino, Villetti; Donofrio, Gaetano. - In: VETERINARY RESEARCH. - ISSN 0928-4249. - 45:(2014), p. 8. [10.1186/1297-9716-45-8]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2761302
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