Cell surface pili have recently been found in many different bifidobacterial species, including the infant gut commensal Bifidobacterium bifidum PRL2010. Pili produced by PRL2010 have been shown to be important molecular mediators for bacterial interaction with its human host. However, nothing is known about the modulation of their expression in response to cues that reflect the gastro intestinal environment, such as thermal, acidic, and osmotic challenges, or the presence of other gut microorganisms. Here, we investigated how different stress conditions that simulate the gastrointestinal niche influence the expression of PRL2010 sortase-dependent pili, and how this may impact on the coexistence and interaction with other human gut commensals.

Expression of sortase-dependent pili of Bifidobacterium bifidum PRL2010 in response to environmental gut conditions / Turroni, Francesca; Serafini, Fausta; Marta, Mangifesta; Stefania, Arioli; Diego, Mora; Douwe van, Sinderen; Ventura, Marco. - In: FEMS MICROBIOLOGY LETTERS. - ISSN 1574-6968. - 357:(2014), pp. 23-33. [10.1111/1574-6968.12509]

Expression of sortase-dependent pili of Bifidobacterium bifidum PRL2010 in response to environmental gut conditions

TURRONI, FRANCESCA;SERAFINI, Fausta;VENTURA, Marco
2014-01-01

Abstract

Cell surface pili have recently been found in many different bifidobacterial species, including the infant gut commensal Bifidobacterium bifidum PRL2010. Pili produced by PRL2010 have been shown to be important molecular mediators for bacterial interaction with its human host. However, nothing is known about the modulation of their expression in response to cues that reflect the gastro intestinal environment, such as thermal, acidic, and osmotic challenges, or the presence of other gut microorganisms. Here, we investigated how different stress conditions that simulate the gastrointestinal niche influence the expression of PRL2010 sortase-dependent pili, and how this may impact on the coexistence and interaction with other human gut commensals.
2014
Expression of sortase-dependent pili of Bifidobacterium bifidum PRL2010 in response to environmental gut conditions / Turroni, Francesca; Serafini, Fausta; Marta, Mangifesta; Stefania, Arioli; Diego, Mora; Douwe van, Sinderen; Ventura, Marco. - In: FEMS MICROBIOLOGY LETTERS. - ISSN 1574-6968. - 357:(2014), pp. 23-33. [10.1111/1574-6968.12509]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2761124
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