Stable core–shell nanospheres self-assemble inwater from heterodimers combining a hydrophobic calix[4]arene moiety and a hydrophilic b-cyclodextrin head; their potential to encapsulate and provide sustained release of the anticancer drug docetaxel and undergo surface post-modification with glycoligands targeting the macrophage mannose receptor is discussed.
Glycoligand-targeted core-shell nanospheres with tunable drug release profiles from calixarene-cyclodextrin heterodimers / Gallego Yerga, L.; Lomazzi, Michela; Sansone, Francesco; Ortiz Mellet, C.; Casnati, Alessandro; García Fernández, J. M.. - In: CHEMICAL COMMUNICATIONS. - ISSN 1359-7345. - 50:(2014), pp. 7440-7443. [10.1039/C4CC02703E]
Glycoligand-targeted core-shell nanospheres with tunable drug release profiles from calixarene-cyclodextrin heterodimers
LOMAZZI, Michela;SANSONE, Francesco;CASNATI, Alessandro;
2014-01-01
Abstract
Stable core–shell nanospheres self-assemble inwater from heterodimers combining a hydrophobic calix[4]arene moiety and a hydrophilic b-cyclodextrin head; their potential to encapsulate and provide sustained release of the anticancer drug docetaxel and undergo surface post-modification with glycoligands targeting the macrophage mannose receptor is discussed.| File | Dimensione | Formato | |
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ChemCommun Fernandez SI.pdf
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ChemCommun Fernandez.pdf
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Tipologia:
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