Water penetration and disintegrating force measurements were combined with the aim of assessing the role played by various mechanisms in the disintegration process. Nine tablet series, made of differing base materials (α-lactose monohydrate, dicalcium phosphate dihydrate and acetylsalicylic acid) such as are likely to elicit differing disintegration mechanisms and containing differing disintegrates in varying percentages were prepared and checked for Water penetration, disintegrating force development and disintegration ...
Water uptake and disintegrating force measurements: towards a general understanding of disintegration mechanisms / C., Caramella; Colombo, Paolo; U., Conte; F., Ferrari; A., La Manna; HV Van, Kamp; Gk, Bolhuis. - In: DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY. - ISSN 0363-9045. - 12:11-13(1986), pp. 1749-1766.
Water uptake and disintegrating force measurements: towards a general understanding of disintegration mechanisms
COLOMBO, Paolo;
1986-01-01
Abstract
Water penetration and disintegrating force measurements were combined with the aim of assessing the role played by various mechanisms in the disintegration process. Nine tablet series, made of differing base materials (α-lactose monohydrate, dicalcium phosphate dihydrate and acetylsalicylic acid) such as are likely to elicit differing disintegration mechanisms and containing differing disintegrates in varying percentages were prepared and checked for Water penetration, disintegrating force development and disintegration ...I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.