Drug constant release is not always the desired solution for controlled drug administration; some therapeutic situations require consecutive pulses of active principle A biphasic oral delivery system able to release an immediate dose of therapeutic agent as well as a further pulse of drug after some hours could be interesting In order to obtain such desired releasing performances, a new system (three layer tablet) has been designed with the following characteristics-an energy source, able to deliver the two divided doses of ...
A new ibuprofen pulsed release oral dosage form / U., Conte; Colombo, Paolo; A., La Manna; A., Gazzaniga; Me, Sangalli; P., Giunchedi. - In: DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY. - ISSN 0363-9045. - 15:14-16(1989), pp. 2583-2596.
A new ibuprofen pulsed release oral dosage form
COLOMBO, Paolo;
1989-01-01
Abstract
Drug constant release is not always the desired solution for controlled drug administration; some therapeutic situations require consecutive pulses of active principle A biphasic oral delivery system able to release an immediate dose of therapeutic agent as well as a further pulse of drug after some hours could be interesting In order to obtain such desired releasing performances, a new system (three layer tablet) has been designed with the following characteristics-an energy source, able to deliver the two divided doses of ...I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.