A previous paper dealt with the preparation of an in vitro programmable zero-order drug delivery system in which the area of the surface exposed to the dissolution medium and the macromolecular relaxation of polymer controlled the release of the drug. In the present study, the preparation of similar delivery systems is described, in which differing drugs and polymers were used to ascertain the mechanism governing the drug-release kinetics. The movement of the interfaces between solvent and system was measured during drug ...
Swelling-activated drug delivery systems / Ubaldo, Conte; Colombo, Paolo; Andrea, Gazzaniga; Maria Edvige, Sangalli; Aldo La, Manna. - In: BIOMATERIALS. - ISSN 0142-9612. - 9:6(1988), pp. 489-493.
Swelling-activated drug delivery systems
COLOMBO, Paolo;
1988-01-01
Abstract
A previous paper dealt with the preparation of an in vitro programmable zero-order drug delivery system in which the area of the surface exposed to the dissolution medium and the macromolecular relaxation of polymer controlled the release of the drug. In the present study, the preparation of similar delivery systems is described, in which differing drugs and polymers were used to ascertain the mechanism governing the drug-release kinetics. The movement of the interfaces between solvent and system was measured during drug ...I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
