Angiotensin, administered by intraperitoneal route (0.1 - 100 micrograms/kg) significantly delayed gastric emptying in the conscious rat. This action, most probably connected with the spasmogenic effect on the gastroduodenal junction, was antagonized by saralasin (125 and 250 micrograms/kg intraperitoneally). Our data seem to suggest an action of the peptide on the stomach mediated through an interaction with specific receptors.
Inhibition of gastric emptying by angiotensin in the rat and its antagonism by saralasin / Scarpignato, Carmelo; Manfredi, G; Starcich, B; Bertaccini, G.. - In: RESEARCH COMMUNICATIONS IN CHEMICAL PATHOLOGY AND PHARMACOLOGY. - ISSN 0034-5164. - 42:2(1983), pp. 335-338.
Inhibition of gastric emptying by angiotensin in the rat and its antagonism by saralasin.
SCARPIGNATO, Carmelo;
1983-01-01
Abstract
Angiotensin, administered by intraperitoneal route (0.1 - 100 micrograms/kg) significantly delayed gastric emptying in the conscious rat. This action, most probably connected with the spasmogenic effect on the gastroduodenal junction, was antagonized by saralasin (125 and 250 micrograms/kg intraperitoneally). Our data seem to suggest an action of the peptide on the stomach mediated through an interaction with specific receptors.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
