The stimulatory effect of vasoactive intestinal peptide (VIP) and secretin has been compared on exocrine pancreatic secretion in anaesthetized cats. Both peptides were given by bolus intravenous injection and continuous intravenous infusion. After bolus injection, VIP stimulated pancreatic secretion only weakly. On the contrary, during intravenous infusion, the maximal effect of VIP did not differ significantly from that of secretin. Therefore, while the potency of VIP is always lower than that of secretin, its efficacy appears to be strictly dependent on the mode of administration.

Comparative effects of vasoactive intestinal peptide and secretin on exocrine pancreatic secretion in the cat / Roche, C; Vagne, M; Scarpignato, Carmelo; Mutt, V.. - In: REGULATORY PEPTIDES. - ISSN 0167-0115. - 12:2(1985), pp. 125-132.

Comparative effects of vasoactive intestinal peptide and secretin on exocrine pancreatic secretion in the cat.

SCARPIGNATO, Carmelo;
1985-01-01

Abstract

The stimulatory effect of vasoactive intestinal peptide (VIP) and secretin has been compared on exocrine pancreatic secretion in anaesthetized cats. Both peptides were given by bolus intravenous injection and continuous intravenous infusion. After bolus injection, VIP stimulated pancreatic secretion only weakly. On the contrary, during intravenous infusion, the maximal effect of VIP did not differ significantly from that of secretin. Therefore, while the potency of VIP is always lower than that of secretin, its efficacy appears to be strictly dependent on the mode of administration.
1985
Comparative effects of vasoactive intestinal peptide and secretin on exocrine pancreatic secretion in the cat / Roche, C; Vagne, M; Scarpignato, Carmelo; Mutt, V.. - In: REGULATORY PEPTIDES. - ISSN 0167-0115. - 12:2(1985), pp. 125-132.
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2520565
Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact