To investigate the permeation of the anti-estrogenic drug tamoxifen through rat intestinal mucosa from tamoxifen-loaded chitosan/lecithin nanoparticles (TAM-NCL) and to study the role of bioadhesion and enzymatic degradation of the TAMNCL in the permeation experiment through the rat intestinal mucus.
Interaction of chitosan/lecithin nanoparticles with the rat intestinal tissue / Barbieri, Stefano; S., Mazzaferro; K., Bouchemal; Sonvico, Fabio; Colombo, Paolo; G., Ponchel. - In: THE AAPS JOURNAL. - ISSN 1550-7416. - 13(S2):(2011), pp. W4114-W4114. (Intervento presentato al convegno 2011 AAPS Annual Meeting tenutosi a Washington D.C. (USA) nel October 23 – 27, 2011).
Interaction of chitosan/lecithin nanoparticles with the rat intestinal tissue
BARBIERI, Stefano;SONVICO, Fabio;COLOMBO, Paolo;
2011-01-01
Abstract
To investigate the permeation of the anti-estrogenic drug tamoxifen through rat intestinal mucosa from tamoxifen-loaded chitosan/lecithin nanoparticles (TAM-NCL) and to study the role of bioadhesion and enzymatic degradation of the TAMNCL in the permeation experiment through the rat intestinal mucus.| File | Dimensione | Formato | |
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