E. capsularis transferred to sporulation medium undergoes two different differentiation processes: formation of a true mycelium and sporulation. Formation of a true mycelium, which occurs during mitotic division, can occur in the absence of 1 st respiration and in the presence of a very low level of mitochondrial translation. Sporulation occurring within both specialized and unspecialized structures of the mycelium, which involves meiosis, requires a full level of both mitochondrial protein synthesis and 1st respiration.
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