A review. Current methods for DNA detection are based on the combined use of labeled probes hybridized to target sequences which are amplified by polymerase chain reaction (PCR). New methods that eliminate the requirement for both PCR and labeling steps could afford faster, cheaper and simpler devices for the anal. of small amts. of unamplified DNA. The results we obtained in the ultrasensitive detection of non-amplified genomic DNA are here described.
Detection of non amplified genomic DNA by advanced SPRI methods / Roberta, D'Agata; Corradini, Roberto; Cristina, Ferretti; Laura Maria, Zanoli; Marcello, Gatti; Marchelli, Rosangela; Giuseppe, Spoto. - In: LA CHIMICA E L'INDUSTRIA. - ISSN 0009-4315. - 92:(2010), pp. 140-145.
Detection of non amplified genomic DNA by advanced SPRI methods
CORRADINI, Roberto;MARCHELLI, Rosangela;
2010-01-01
Abstract
A review. Current methods for DNA detection are based on the combined use of labeled probes hybridized to target sequences which are amplified by polymerase chain reaction (PCR). New methods that eliminate the requirement for both PCR and labeling steps could afford faster, cheaper and simpler devices for the anal. of small amts. of unamplified DNA. The results we obtained in the ultrasensitive detection of non-amplified genomic DNA are here described.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
