A review. Current methods for DNA detection are based on the combined use of labeled probes hybridized to target sequences which are amplified by polymerase chain reaction (PCR). New methods that eliminate the requirement for both PCR and labeling steps could afford faster, cheaper and simpler devices for the anal. of small amts. of unamplified DNA. The results we obtained in the ultrasensitive detection of non-amplified genomic DNA are here described.
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