Diffuse brown pigmentation of the buccal mucosa and tongue.

A 52-year-old white woman was referred by her family physician to the Unit of Odontostomatology at the University Hospital of Parma, Italy. She complained about the presence of a dark alteration of her oral mucosa, especially on her cheeks and the ventral surface of her tongue. Her family physician had discovered the oral pigmentation during a general checkup two months previously. Her medical history disclosed positivity for hepatitis C virus, as well as long-term therapeutic regimens of a calcium channel blocker (amlodipine) and a proton pump inhibitor (lansoprazole). She denied tobacco use in any form.