During apoptosis, nuclear pores undergo strong modifications, which are described here in five different apoptotic models. Conventional electron microscopy, supported by freeze-fracture analysis, showed a constant migration of nuclear pores towards the diffuse chromatin areas. In contrast, dense chromatin areas appear pore-free and are frequently surrounded by strongly dilated cisternae. A possible functional significance of this pore behaviour during apoptosis is discussed.
Nuclear pores in the apoptotic cell / FALCIERI E.; GOBBI P.; CATALDI A.; ZAMAI L.; FAENZA I.; VITALE M.. - In: HISTOCHEMICAL JOURNAL. - ISSN 0018-2214. - 26(9)(1994), pp. 754-763.
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