Twenty-five patients with rheumatoid arthritis (RA) who developed toxicity while taking remission inducing drugs and 30 without toxicity were studied for possible associations with class I and II HLA antigens. A strong association has been found between nephritis and dermatitis due to Tiopronin (a D-Penicillamine like compound) and class I antigens B35-Cw4, and between dermatitis due to gold thiosulphate and B35. Compared to healthy controls a lower DR5 frequency was observed in patients with RA except for the Tiopronin related nephritis group.

Toxicity due to remission inducing drugs in rheumatoid arthritis. Association with HLA-B35 and Cw4 antigens / G., Ferraccioli; F., Peri; A., Nervetti; U., Ambanelli; Savi, Mario. - In: THE JOURNAL OF RHEUMATOLOGY. - ISSN 0315-162X. - Feb13(1):(1986), pp. 65-68.

Toxicity due to remission inducing drugs in rheumatoid arthritis. Association with HLA-B35 and Cw4 antigens.

SAVI, Mario
1986-01-01

Abstract

Twenty-five patients with rheumatoid arthritis (RA) who developed toxicity while taking remission inducing drugs and 30 without toxicity were studied for possible associations with class I and II HLA antigens. A strong association has been found between nephritis and dermatitis due to Tiopronin (a D-Penicillamine like compound) and class I antigens B35-Cw4, and between dermatitis due to gold thiosulphate and B35. Compared to healthy controls a lower DR5 frequency was observed in patients with RA except for the Tiopronin related nephritis group.
1986
Toxicity due to remission inducing drugs in rheumatoid arthritis. Association with HLA-B35 and Cw4 antigens / G., Ferraccioli; F., Peri; A., Nervetti; U., Ambanelli; Savi, Mario. - In: THE JOURNAL OF RHEUMATOLOGY. - ISSN 0315-162X. - Feb13(1):(1986), pp. 65-68.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2427598
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