The interaction of 8-methoxypsoralen (8-MOP) with synthetic eumelanin was investigated using static and time-resolved fluoresence and pulsed photoacoustic calorimetry. Spectroscopic data indicate the absence of interaction in the ground state, whereas the singlet excited state of 8-MOP is quenched by the pigment; the average fluorescence lifetimes are independent of the melanin concentration, thus indicating a static mechanism. Photoacoustic data show that the quenching process involves an increased intersystem crossing probability, which is almost unaffected by the presence of oxygen, as expected for a molecule essentially acting as a type I photosensitizing agent.

Quenching of the excited states of 8-methoxypsoralen by synthetic eumelanin / A. Losi; C. Viappiani; P.R. Crippa. - In: JOURNAL OF FLUORESCENCE. - ISSN 1053-0509. - 3(1993), pp. 191-194. [10.1007/BF00862741]

Quenching of the excited states of 8-methoxypsoralen by synthetic eumelanin

LOSI, Aba;VIAPPIANI, Cristiano;
1993

Abstract

The interaction of 8-methoxypsoralen (8-MOP) with synthetic eumelanin was investigated using static and time-resolved fluoresence and pulsed photoacoustic calorimetry. Spectroscopic data indicate the absence of interaction in the ground state, whereas the singlet excited state of 8-MOP is quenched by the pigment; the average fluorescence lifetimes are independent of the melanin concentration, thus indicating a static mechanism. Photoacoustic data show that the quenching process involves an increased intersystem crossing probability, which is almost unaffected by the presence of oxygen, as expected for a molecule essentially acting as a type I photosensitizing agent.
Quenching of the excited states of 8-methoxypsoralen by synthetic eumelanin / A. Losi; C. Viappiani; P.R. Crippa. - In: JOURNAL OF FLUORESCENCE. - ISSN 1053-0509. - 3(1993), pp. 191-194. [10.1007/BF00862741]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11381/2393135
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