A molecularly imprinted polymer with trinitrotoluene as the template molecule was synthesized and used asthe novel coating for solid-phase microextraction of the nitroaromatic explosive 2,4,6-trinitrotoluene for its selective determination. The fiber was characterized in terms of coating thickness, morphology, intra- and inter-batch repeatability and extraction efficiency. An average thickness of 50 ±4 μm with a uniform distribution of the coating was obtained. Good performances of the developed procedure in term of both intra-batch and inter-batch repeatability withrelative standard deviations <8% were obtained. Finally, detection and quantitation limits in the low nanogram per kilogram levels were achieved proving the superiorextraction capability of the developed coating, obtaining gas chromatography-mass spectrometry responses about two times higher than those achieved using commercial devices.

Solid phase microextraction of 2,4,6-trinitrotoluene using a molecularly imprinted-based fiber / F. Bianchi; M. Giannetto; G. Mori; G. D’Agostino; M. Careri; A. Mangia. - In: ANALYTICAL AND BIOANALYTICAL CHEMISTRY. - ISSN 1618-2642. - 403:(2012), pp. 2411-2418. [10.1007/s00216-012-5875-0]

Solid phase microextraction of 2,4,6-trinitrotoluene using a molecularly imprinted-based fiber

BIANCHI, Federica;GIANNETTO, Marco;MORI, Giovanni;CARERI, Maria;MANGIA, Alessandro
2012

Abstract

A molecularly imprinted polymer with trinitrotoluene as the template molecule was synthesized and used asthe novel coating for solid-phase microextraction of the nitroaromatic explosive 2,4,6-trinitrotoluene for its selective determination. The fiber was characterized in terms of coating thickness, morphology, intra- and inter-batch repeatability and extraction efficiency. An average thickness of 50 ±4 μm with a uniform distribution of the coating was obtained. Good performances of the developed procedure in term of both intra-batch and inter-batch repeatability withrelative standard deviations <8% were obtained. Finally, detection and quantitation limits in the low nanogram per kilogram levels were achieved proving the superiorextraction capability of the developed coating, obtaining gas chromatography-mass spectrometry responses about two times higher than those achieved using commercial devices.
Solid phase microextraction of 2,4,6-trinitrotoluene using a molecularly imprinted-based fiber / F. Bianchi; M. Giannetto; G. Mori; G. D’Agostino; M. Careri; A. Mangia. - In: ANALYTICAL AND BIOANALYTICAL CHEMISTRY. - ISSN 1618-2642. - 403:(2012), pp. 2411-2418. [10.1007/s00216-012-5875-0]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11381/2392131
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