During the last decade, a significant body of evidence has accumulated, indicating that the declining activity of the GH-IGF-I axis with aging might play a role in the development of frailty and in several pathological conditions commonly seen during aging, such as atherosclerosis, cardiovascular disease, and cognitive decline. GH therapy has become widely popular as antiaging therapy in order to counteract the age-related decline in muscle mass and strength and the increase in fat mass. However there are only few proven beneficial effects of GH therapy in healthy elderly subjects and its use remains highly controversial in the scientific community. In this paper we will review the current evidence related to the use of GH and/or GH-secretagogues in normal and pathological aging. (www.actabiomedica.it)

Update on new therapeutic options for the somatopause / Ceda, Gian Paolo; Dall'Aglio, Elisabetta; Morganti, S.; Denti, L.; Maggio, Marcello Giuseppe; Lauretani, F.; Artoni, A.; Ceresini, Graziano; Cattabiani, Chiara; Valenti, Giorgio. - In: ACTA BIO-MEDICA DE L'ATENEO PARMENSE. - ISSN 0392-4203. - 81 suppl 1:(2010), pp. 67-72.

Update on new therapeutic options for the somatopause

CEDA, Gian Paolo;DALL'AGLIO, Elisabetta;MAGGIO, Marcello Giuseppe;F. Lauretani;CERESINI, Graziano;CATTABIANI, Chiara;VALENTI, Giorgio
2010-01-01

Abstract

During the last decade, a significant body of evidence has accumulated, indicating that the declining activity of the GH-IGF-I axis with aging might play a role in the development of frailty and in several pathological conditions commonly seen during aging, such as atherosclerosis, cardiovascular disease, and cognitive decline. GH therapy has become widely popular as antiaging therapy in order to counteract the age-related decline in muscle mass and strength and the increase in fat mass. However there are only few proven beneficial effects of GH therapy in healthy elderly subjects and its use remains highly controversial in the scientific community. In this paper we will review the current evidence related to the use of GH and/or GH-secretagogues in normal and pathological aging. (www.actabiomedica.it)
2010
Update on new therapeutic options for the somatopause / Ceda, Gian Paolo; Dall'Aglio, Elisabetta; Morganti, S.; Denti, L.; Maggio, Marcello Giuseppe; Lauretani, F.; Artoni, A.; Ceresini, Graziano; Cattabiani, Chiara; Valenti, Giorgio. - In: ACTA BIO-MEDICA DE L'ATENEO PARMENSE. - ISSN 0392-4203. - 81 suppl 1:(2010), pp. 67-72.
File in questo prodotto:
File Dimensione Formato  
Paper Ceda.pdf

non disponibili

Tipologia: Documento in Post-print
Licenza: Creative commons
Dimensione 197.6 kB
Formato Adobe PDF
197.6 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2380050
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 9
  • ???jsp.display-item.citation.isi??? ND
social impact