We present a new approach for developing a label-free biosensor for detection of DNA. The biosensor based on a biofunctionalized Double Tilt Fiber Bragg Grating transduces the presence of DNA into a change of visibility of fringes of its interference spectrum. Real-time spectral measurement results are reported, showing that a 10nM DNA solution induces a 10% modulation of the corresponding fringes visibility.
Double tilted fiber Bragg gratings for label-free DNA detection / Candiani, A., P., C., S., P., Sozzi, M., Coscelli, E., Poli, F., Cucinotta, A., Selleri, S., R., V., Corradini, R., Marchelli, R.. - (2011), pp. 1-3. (2011 International Workshop on Biophotonics Parma, Italy June 8-10, 2011) [10.1109/IWBP.2011.5954849].
Double tilted fiber Bragg gratings for label-free DNA detection
CANDIANI, Alessandro;SOZZI, MICHELE;COSCELLI, Enrico;POLI, Federica;CUCINOTTA, Annamaria;SELLERI, Stefano;CORRADINI, Roberto;MARCHELLI, Rosangela
2011-01-01
Abstract
We present a new approach for developing a label-free biosensor for detection of DNA. The biosensor based on a biofunctionalized Double Tilt Fiber Bragg Grating transduces the presence of DNA into a change of visibility of fringes of its interference spectrum. Real-time spectral measurement results are reported, showing that a 10nM DNA solution induces a 10% modulation of the corresponding fringes visibility.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
