To evaluate and compare histogram features (mean lung attenuation, skewness, kurtosis) of low-dose and standard-dose CT in a group of patients affected by idiopathic interstitial pneumonitis.We analyzed 16 patients affected by idiopathic interstitial pneumonitis. Spiral whole lung thin-section CT acquisition at standard dose (100 mAs) and three additional low-dose (50 mAs) CT images were obtained. After obtained frequency histograms, mean lung attenuation (MLA), skewness and kurtosis and three range of density (-700/-200 HU; -700/-400 HU; -500/-200 HU) of the standard-and low-dose thin-section CT scans were analyzed and compared.The parameters obtained with low-dose and standard-dose spiral CT were correlated in a highly significant manner and were equivalent (p<0.01). The greatest correlation was found between standard-and low-dose kurtosis and standard and low-dose -700/-400 HU subrange of density (r=0.92; p<0.0001).Our results prove that a quantitative CT objective evaluation in lung fibrosis can be successfully obtained with low-dose spiral CT, with reduced mA.

Evaluation of quantitative CT indexes in idiopathic interstitial pneumonitis using a low-dose technique / Sverzellati, Nicola; Zompatori, Maurizio; De Luca, Giovanni; Chetta, Alfredo A; Bnà, Claudio; Ormitti, Francesca; Cobelli, Rocco. - In: EUROPEAN JOURNAL OF RADIOLOGY. - ISSN 0720-048X. - 56:3(2005), pp. 370-375. [10.1016/j.ejrad.2005.05.012]

Evaluation of quantitative CT indexes in idiopathic interstitial pneumonitis using a low-dose technique.

SVERZELLATI, Nicola;CHETTA, Alfredo Antonio;
2005

Abstract

To evaluate and compare histogram features (mean lung attenuation, skewness, kurtosis) of low-dose and standard-dose CT in a group of patients affected by idiopathic interstitial pneumonitis.We analyzed 16 patients affected by idiopathic interstitial pneumonitis. Spiral whole lung thin-section CT acquisition at standard dose (100 mAs) and three additional low-dose (50 mAs) CT images were obtained. After obtained frequency histograms, mean lung attenuation (MLA), skewness and kurtosis and three range of density (-700/-200 HU; -700/-400 HU; -500/-200 HU) of the standard-and low-dose thin-section CT scans were analyzed and compared.The parameters obtained with low-dose and standard-dose spiral CT were correlated in a highly significant manner and were equivalent (p<0.01). The greatest correlation was found between standard-and low-dose kurtosis and standard and low-dose -700/-400 HU subrange of density (r=0.92; p<0.0001).Our results prove that a quantitative CT objective evaluation in lung fibrosis can be successfully obtained with low-dose spiral CT, with reduced mA.
Evaluation of quantitative CT indexes in idiopathic interstitial pneumonitis using a low-dose technique / Sverzellati, Nicola; Zompatori, Maurizio; De Luca, Giovanni; Chetta, Alfredo A; Bnà, Claudio; Ormitti, Francesca; Cobelli, Rocco. - In: EUROPEAN JOURNAL OF RADIOLOGY. - ISSN 0720-048X. - 56:3(2005), pp. 370-375. [10.1016/j.ejrad.2005.05.012]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11381/2338451
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