We report the features of non-length dependent small fiber neuropathy (SFN) and compare them to those with distal length-dependent SFN. In a series of 224 consecutive neuropathy patients, we evaluated 44 patients with SFN diagnosed in the presence of both symptoms and signs. Eleven were classified as non-length dependent SFN. Disease associations were Sjögren's syndrome (two patients), impaired glucose tolerance, rheumatoid arthritis, hepatitis C virus, Crohn's disease, and idiopathic (five patients). In the 33 patients with distal SFN, the age of onset was significantly older and more had impaired glucose metabolism (16/33). In both groups, pain was mainly characterized as burning, but patients with non-length dependent SFN more often reported an "itchy" quality and allodynia to light touch.
Non-length dependent small fiber neuropathy. A prospective case series / Gemignani, Franco; Giovanelli, M.; Vitetta, F.; Santilli, D.; Bellanova, M. F.; Brindani, F.; Marbini, A.. - In: JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM. - ISSN 1529-8027. - 15(1):(2010), pp. 55-61. [10.1111/j.1529-8027.2010.00252.x]
Non-length dependent small fiber neuropathy. A prospective case series
GEMIGNANI, Franco;
2010-01-01
Abstract
We report the features of non-length dependent small fiber neuropathy (SFN) and compare them to those with distal length-dependent SFN. In a series of 224 consecutive neuropathy patients, we evaluated 44 patients with SFN diagnosed in the presence of both symptoms and signs. Eleven were classified as non-length dependent SFN. Disease associations were Sjögren's syndrome (two patients), impaired glucose tolerance, rheumatoid arthritis, hepatitis C virus, Crohn's disease, and idiopathic (five patients). In the 33 patients with distal SFN, the age of onset was significantly older and more had impaired glucose metabolism (16/33). In both groups, pain was mainly characterized as burning, but patients with non-length dependent SFN more often reported an "itchy" quality and allodynia to light touch.File | Dimensione | Formato | |
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