The possibility to exploit all-silica hollow-core microstructured Bragg fibers to realize a biosensor useful to detect theDNAhybridization process has been investigated.ABragg fiber recently fabricated has been considered for the analysis performed by means of a full-vector modal solver based on the finite-element method. Since the DNA molecules necessary for the biosensor realization are in aqueous solution, it has been taken into account a microstructured fiber with water-filled holes. The dispersion curve and the confinement loss spectrum have been calculated in order to understand how a biofilm layer on the inner surface of the fiber holes can modify the fundamental mode properties. The numerical analysis results have successfully demonstrated the DNA bio-sensor feasibility in hollow-core Bragg fibers.
All-silica hollow-core microstructured Bragg fibers for bio-sensor application / PASSARO D.; M. FORONI; F. POLI; A. CUCINOTTA; S. SELLERI; J. LAEGSGAARD; A. BJARKLEV. - In: IEEE SENSORS JOURNAL. - ISSN 1530-437X. - 8(2008), pp. 1280-1286. [10.1109/JSEN.2008.926969]