Myeloma or Kahler-Bozzolo disease represents around 1% of all malignant tumors and 10% of the haematological variety; it is a B-lymphocellular malignant neoplasia which originates from plasma cells that produce monoclonal immunoglobulin, infiltrating in and destroying the adjacent bone tissue.Myeloma may be distinguished at radiological imaging in four distinct types: single osseous lesions (solitary plasmacytoma), diffused skeletal effects (myelomatosis), diffused osteopenia and sclerosing myeloma. It is known that initial osteolysis may not be shown through radiographic examination or CT; the lysis only becomes evident when there is a bone loss of over 50%, usually in the presence of a =/> 0,5 cm focal lesion.We present here the clinical-radiological aspects of a solitary bone plasmacitoma (SBP) of the knee of a 35 year old male which was not evidenced at radiological examination or CT but was evident as a 3 cm focal alteration at MR. The lesion was confirmed by PET and the histological diagnosis was performed by a CT guided bioptic sample.

Occult large epiphyseal solitary plasmocitoma at multidetector row computer tomography detected by magnetic resonance imaging / De Filippo, Massimo; Pogliacomi, Francesco; Albissinni, Ugo; Quinto, Salvatore; Bocchi, Carlo; Sverzellati, Nicola; Lipia, Stefano; Zompatori, Maurizio. - In: ACTA BIO-MEDICA DE L'ATENEO PARMENSE. - ISSN 0392-4203. - 79:3(2008), pp. 240-245.

Occult large epiphyseal solitary plasmocitoma at multidetector row computer tomography detected by magnetic resonance imaging.

DE FILIPPO, Massimo;POGLIACOMI, Francesco;SVERZELLATI, Nicola;
2008

Abstract

Myeloma or Kahler-Bozzolo disease represents around 1% of all malignant tumors and 10% of the haematological variety; it is a B-lymphocellular malignant neoplasia which originates from plasma cells that produce monoclonal immunoglobulin, infiltrating in and destroying the adjacent bone tissue.Myeloma may be distinguished at radiological imaging in four distinct types: single osseous lesions (solitary plasmacytoma), diffused skeletal effects (myelomatosis), diffused osteopenia and sclerosing myeloma. It is known that initial osteolysis may not be shown through radiographic examination or CT; the lysis only becomes evident when there is a bone loss of over 50%, usually in the presence of a =/> 0,5 cm focal lesion.We present here the clinical-radiological aspects of a solitary bone plasmacitoma (SBP) of the knee of a 35 year old male which was not evidenced at radiological examination or CT but was evident as a 3 cm focal alteration at MR. The lesion was confirmed by PET and the histological diagnosis was performed by a CT guided bioptic sample.
File in questo prodotto:
File Dimensione Formato  
24 plasmocitoma Acta Biomedica 2008.pdf

non disponibili

Tipologia: Altro materiale allegato
Licenza: Creative commons
Dimensione 317.37 kB
Formato Adobe PDF
317.37 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11381/2279867
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 4
  • ???jsp.display-item.citation.isi??? ND
social impact