The present invention relates to an immunogenic polypeptide comprising a) a scaffold polypeptide, and b) a L2 polypeptide or a fragment of said L2 polypeptide, wherein said scaffold polypeptide constrains the structure of said L2 polypeptide, or of a fragment of said L2 polypeptide. Moreover, the present invention relates to a vaccine comprising said immunogenic polypeptide. The present invention is also concerned with a method for producing an antibody against human papillomavirus. Also encompassed by the present invention is an antibody obtained by carrying out the said method.

IMMUNOGENIC POLYPEPTIDES COMPRISING A SCAFFOLD POLYPEPTIDE AND A L2 POLYPEPTIDE OR FRAGMENT THEREOF (EP2376525B1) / Bolchi, Angelo; Ottonello, Simone; Rubio, I; Tommasino, M; Muller, M.. - ELETTRONICO. - (2017).

IMMUNOGENIC POLYPEPTIDES COMPRISING A SCAFFOLD POLYPEPTIDE AND A L2 POLYPEPTIDE OR FRAGMENT THEREOF (EP2376525B1)

BOLCHI, Angelo;OTTONELLO, Simone;
2017-01-01

Abstract

The present invention relates to an immunogenic polypeptide comprising a) a scaffold polypeptide, and b) a L2 polypeptide or a fragment of said L2 polypeptide, wherein said scaffold polypeptide constrains the structure of said L2 polypeptide, or of a fragment of said L2 polypeptide. Moreover, the present invention relates to a vaccine comprising said immunogenic polypeptide. The present invention is also concerned with a method for producing an antibody against human papillomavirus. Also encompassed by the present invention is an antibody obtained by carrying out the said method.
2017
IMMUNOGENIC POLYPEPTIDES COMPRISING A SCAFFOLD POLYPEPTIDE AND A L2 POLYPEPTIDE OR FRAGMENT THEREOF (EP2376525B1) / Bolchi, Angelo; Ottonello, Simone; Rubio, I; Tommasino, M; Muller, M.. - ELETTRONICO. - (2017).
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/1895320
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