We thank Schlaich et al. for their  useful comments on our recent paper . We agree that there is no doubt that nitric oxidemediated, endothelium-dependent mechanisms play a key role in alterations of renal haemodynamics induced in humans by systemic L-arginine infusion, which remains an important tool of research in that field . Such changes, however, may not be considered solely as a measure of the endothelial control of kidney circulation, but reflect a more complex sequence of events, including changes in tubulo-glomerular feedback (TGF).
Measuring endothelial dysfunction - Reply / A. MONTANARI; A. NOVARINI; BIGGI A.. - In: JOURNAL OF HYPERTENSION. - ISSN 0263-6352. - 25 N°7(2007), pp. 1516-1517. [10.1097/HJH.0b013e3281c4a030]