A simple and efficient approach to selectively obtain 2,4(5)-diarylimidazoles suppressing formation of 2-aroyl-4(5)-arylimidazoles is described. The yield of each of the two products strongly depends on the reaction conditions employed. This reaction provides a simple method to prepare small libraries of biologically active compounds by parallel synthesis.
A Practical Synthesis of 2,4(5)-Diarylimidazoles from Simple Building Blocks / Zuliani, Valentina; Cocconcelli, G.; Fantini, M.; Ghiron, C.; Rivara, Mirko. - In: JOURNAL OF ORGANIC CHEMISTRY. - ISSN 0022-3263. - 72:(2007), pp. 4551-4553. [10.1021/jo070187d]
A Practical Synthesis of 2,4(5)-Diarylimidazoles from Simple Building Blocks
ZULIANI, Valentina;RIVARA, Mirko
2007-01-01
Abstract
A simple and efficient approach to selectively obtain 2,4(5)-diarylimidazoles suppressing formation of 2-aroyl-4(5)-arylimidazoles is described. The yield of each of the two products strongly depends on the reaction conditions employed. This reaction provides a simple method to prepare small libraries of biologically active compounds by parallel synthesis.| File | Dimensione | Formato | |
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