Primary oral malignant melanoma (OMM) is a rare neoplasm, accounting for 0.5% of all oral malignancies. The etiology is unknown; tobacco use and chronic irritation may play some role. Clinically, OMM may mimick other pigmented lesions. A biopsy is required in order to establish the diagnosis. The reported risk of malignant cells spreading during invasive procedures and factors such as size of the lesion or anatomical limitations, may influence the diagnostic surgical procedure. Therapy of OMM is commonly based on surgical excision of the primary tumour, supplemented by radiotherapy, with chemotherapy and immunotherapy serving as adjuncts. Prognosis is poor, with a 5-year survival rate of approximately 15%.

Oral malignant melanoma: A review of the literature / Meleti, Marco; RENE LEEMANS, C.; Mooi, W. J.; Vescovi, Paolo; VAN DER WAAL, I.. - In: ORAL ONCOLOGY. - ISSN 1368-8375. - 43(2):(2007), pp. 116-121. [10.1016/j.oraloncology.2006.04.001]

Oral malignant melanoma: A review of the literature.

MELETI, Marco;VESCOVI, Paolo;
2007-01-01

Abstract

Primary oral malignant melanoma (OMM) is a rare neoplasm, accounting for 0.5% of all oral malignancies. The etiology is unknown; tobacco use and chronic irritation may play some role. Clinically, OMM may mimick other pigmented lesions. A biopsy is required in order to establish the diagnosis. The reported risk of malignant cells spreading during invasive procedures and factors such as size of the lesion or anatomical limitations, may influence the diagnostic surgical procedure. Therapy of OMM is commonly based on surgical excision of the primary tumour, supplemented by radiotherapy, with chemotherapy and immunotherapy serving as adjuncts. Prognosis is poor, with a 5-year survival rate of approximately 15%.
2007
Oral malignant melanoma: A review of the literature / Meleti, Marco; RENE LEEMANS, C.; Mooi, W. J.; Vescovi, Paolo; VAN DER WAAL, I.. - In: ORAL ONCOLOGY. - ISSN 1368-8375. - 43(2):(2007), pp. 116-121. [10.1016/j.oraloncology.2006.04.001]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/1513284
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