Biologically active Vancomycin antibiotic mimics have been synthesized by linking two opposite aromatic nuclei of a calix[4]arene derivative in the cone conformation with a polifunctional bridge containing D- or L- alanine units and a diethylentriamine segment.

Synthesis, Antimicrobial Activity and Binding Properties of Calix[4]arenes Based Vancomycin Mimics / A. CASNATI; M. FABBI; N. PELIZZI; A. POCHINI; F. SANSONE; R. UNGARO; E. DI MODUGNO; G. TARZIA. - In: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. - ISSN 0960-894X. - 6(1996), pp. 2699-2704.

Synthesis, Antimicrobial Activity and Binding Properties of Calix[4]arenes Based Vancomycin Mimics

CASNATI, Alessandro;POCHINI, Andrea;SANSONE, Francesco;UNGARO, Rocco;
1996

Abstract

Biologically active Vancomycin antibiotic mimics have been synthesized by linking two opposite aromatic nuclei of a calix[4]arene derivative in the cone conformation with a polifunctional bridge containing D- or L- alanine units and a diethylentriamine segment.
File in questo prodotto:
File Dimensione Formato  
BMCL96.pdf

non disponibili

Tipologia: Documento in Post-print
Licenza: Creative commons
Dimensione 266.09 kB
Formato Adobe PDF
266.09 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11381/1508250
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 119
  • ???jsp.display-item.citation.isi??? 118
social impact