Biologically active Vancomycin antibiotic mimics have been synthesized by linking two opposite aromatic nuclei of a calix[4]arene derivative in the cone conformation with a polifunctional bridge containing D- or L- alanine units and a diethylentriamine segment.
Synthesis, Antimicrobial Activity and Binding Properties of Calix[4]arenes Based Vancomycin Mimics / Casnati, Alessandro; M., Fabbi; N., Pelizzi; Pochini, Andrea; Sansone, Francesco; Ungaro, Rocco; E., DI MODUGNO; G., Tarzia. - In: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. - ISSN 0960-894X. - 6:(1996), pp. 2699-2704.
Synthesis, Antimicrobial Activity and Binding Properties of Calix[4]arenes Based Vancomycin Mimics
CASNATI, Alessandro;POCHINI, Andrea;SANSONE, Francesco;UNGARO, Rocco;
1996-01-01
Abstract
Biologically active Vancomycin antibiotic mimics have been synthesized by linking two opposite aromatic nuclei of a calix[4]arene derivative in the cone conformation with a polifunctional bridge containing D- or L- alanine units and a diethylentriamine segment.File in questo prodotto:
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