Studies of the physiological actions of melatonin have been hindered by the lack of specific, potent and subtype selective agonists and antagonists. This paper reviews our progress in developing subtype selective melatonin antagonists. Evidence is presented suggesting the structural features conferring MT2 selective antagonism.
Strategies leading to MT2 selective melatonin receptor antagonists / Spadoni, G; Bedini, A; Piersanti, G; Mor, Marco; Rivara, Silvia; Tarzia, G.. - STAMPA. - 527:(2003), pp. 577-585. (Intervento presentato al convegno 10th International Meeting of the International-Study-Group-for-Tryptophan-Research (ISTRY) tenutosi a Padova nel 25-29 giugno 2002).
Strategies leading to MT2 selective melatonin receptor antagonists.
MOR, Marco;RIVARA, Silvia;
2003-01-01
Abstract
Studies of the physiological actions of melatonin have been hindered by the lack of specific, potent and subtype selective agonists and antagonists. This paper reviews our progress in developing subtype selective melatonin antagonists. Evidence is presented suggesting the structural features conferring MT2 selective antagonism.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
