A chemometric approach based on experimental design and desirability functions was used to develop and validate a SPME-GC-ICP-MS method for the determination of the organotin compounds dimethyltin, tributyltin and dibuthyltin. Three different SPME coatings were evaluated, obtaining the best results by using the divinylbenzene/carboxen/polydimethylsiloxane 2 cm 50/30 mm fibre. The optimal extraction conditions were found to be the following: T ¼ 30 1C, t ¼ 40 min and pH ¼ 4. Method validation was performed by determining the most relevant quality parameters such as detection limit, quantitation limit, repeatability and intermediate precision. LOD values in the 0.2–8 ng L_1 were obtained.

Optimization of the solid phase microextraction procedure for the ultra-trace determination of organotin compounds by gas chromatography-inductively coupled plasma-mass spectrometry / Bianchi, Federica; Careri, Maria; Maffini, Monica; Mangia, Alessandro; Mucchino, Claudio. - In: JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY. - ISSN 0267-9477. - 21(2006), pp. 970-973. [10.1039/b603310e]

Optimization of the solid phase microextraction procedure for the ultra-trace determination of organotin compounds by gas chromatography-inductively coupled plasma-mass spectrometry

BIANCHI, Federica;CARERI, Maria;MAFFINI, Monica;MANGIA, Alessandro;MUCCHINO, Claudio
2006

Abstract

A chemometric approach based on experimental design and desirability functions was used to develop and validate a SPME-GC-ICP-MS method for the determination of the organotin compounds dimethyltin, tributyltin and dibuthyltin. Three different SPME coatings were evaluated, obtaining the best results by using the divinylbenzene/carboxen/polydimethylsiloxane 2 cm 50/30 mm fibre. The optimal extraction conditions were found to be the following: T ¼ 30 1C, t ¼ 40 min and pH ¼ 4. Method validation was performed by determining the most relevant quality parameters such as detection limit, quantitation limit, repeatability and intermediate precision. LOD values in the 0.2–8 ng L_1 were obtained.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11381/1499386
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