Mucocutaneous leishmaniasis: report of a case with massive involvement of nasal, pharyngeal and laryngeal mucosa.

Mucocutaneous leishmaniasis: report of a case with massive involvement of nasal, pharyngeal and laryngeal mucosa F. Di Lella1, , , V. Vincenti1, D. Zennaro2, A. Afeltra2, A. Baldi3, D. Giordano1, E. Pasanisi1, A. Bacciu1, S. Bacciu1, G. Di Lella4 1 Department of Otolaryngology, University of Parma, Parma, Italy 2 Department of Allergology and Immunology, Campus Bio Medico University, Rome, Italy 3 Department of Biochemistry, Section of Pathology, Second University of Naples, Naples, Italy 4 Department of Oral and Maxillofacial Surgery, S. Giovanni-Addolorata Hospital, Rome, Italy Accepted 17 February 2006. Available online 30 March 2006. http://dx.doi.org/10.1016/j.ijom.2006.02.015, How to Cite or Link Using DOIPermissions & Reprints Leishmaniasis is a protozoal disease transmitted by sandflies. The disease may present in 1 of 3 forms, visceral, cutaneous or mucocutaneous leishmaniasis (MCL), depending mainly on the infecting species and the host immune response. Reported here is a case of mucocutaneous leishmaniasis due to Leishmania brazilienzis in an Italian citizen who lived in Latin America and whose mucosal lesion appeared years after he returned to Italy. Lesions widely involved nasal, pharyngeal, laryngeal and tracheal mucosa. Treatment with liposomal amphotericine B led to almost complete resolution of the lesions and regression of related symptoms; the patient is still followed as an outpatient.