The pathophysiology of spontaneous cervical artery dissection (sCAD) is largely unknown. An association with migraine has been suggested, but not definitively proven. In the setting of a hospital-based prospective case-control study we assessed personal and family history of migraine in 72 patients with sCAD, 72 patients with cerebral infarct unrelated to a CAD (non-CAD) and 72 control subjects. Personal history of migraine was significantly associated to sCAD compared to non-CAD (59.7% vs. 30.6%; OR 3.14; 95% CI 1.41-7.01) and controls (18.1%; OR 7.41; 95% CI 3.11-17.64). As opposed to migraine with aura, migraine without aura was significantly more frequent among sCAD than among non-CAD (56.9% vs. 25.0%; OR 3.91; 95% CI 1.71-8.90) and controls (12.5%; OR 9.84; 95% CI 3.85-25.16). Similar results were observed when the frequencies of family history of migraine were compared. These findings are consistent with the hypothesis that migraine may represent a predisposing condition for sCAD.

History of migraine and the risk of spontaneous cervical artery dissection / Pezzini, A.; Granella, Franco; Grassi, M.; Bertolino, C.; Del Zotto, E.; Immovilli, P.; Bazzoli, E.; Padovani, A.; Zanferrari, C.. - In: CEPHALALGIA. - ISSN 0333-1024. - 25(8):(2005), pp. 575-580. [10.1111/j.1468-2982.2005.00919.x]

History of migraine and the risk of spontaneous cervical artery dissection

Pezzini A.;GRANELLA, Franco;
2005-01-01

Abstract

The pathophysiology of spontaneous cervical artery dissection (sCAD) is largely unknown. An association with migraine has been suggested, but not definitively proven. In the setting of a hospital-based prospective case-control study we assessed personal and family history of migraine in 72 patients with sCAD, 72 patients with cerebral infarct unrelated to a CAD (non-CAD) and 72 control subjects. Personal history of migraine was significantly associated to sCAD compared to non-CAD (59.7% vs. 30.6%; OR 3.14; 95% CI 1.41-7.01) and controls (18.1%; OR 7.41; 95% CI 3.11-17.64). As opposed to migraine with aura, migraine without aura was significantly more frequent among sCAD than among non-CAD (56.9% vs. 25.0%; OR 3.91; 95% CI 1.71-8.90) and controls (12.5%; OR 9.84; 95% CI 3.85-25.16). Similar results were observed when the frequencies of family history of migraine were compared. These findings are consistent with the hypothesis that migraine may represent a predisposing condition for sCAD.
2005
History of migraine and the risk of spontaneous cervical artery dissection / Pezzini, A.; Granella, Franco; Grassi, M.; Bertolino, C.; Del Zotto, E.; Immovilli, P.; Bazzoli, E.; Padovani, A.; Zanferrari, C.. - In: CEPHALALGIA. - ISSN 0333-1024. - 25(8):(2005), pp. 575-580. [10.1111/j.1468-2982.2005.00919.x]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/1445321
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