PALA, Daniele
PALA, Daniele
Dipartimento di Farmacia (attivo dal 20/07/2012 al 31/12/2016)
270 Discovery, development and optimization of low molecular weight EPH–ephrin protein–protein inhibitors
2014-01-01 Tognolini, Massimiliano; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Barocelli, Elisabetta; Mor, Marco; Pala, Daniele; Russo, Simonetta; Incerti, Matteo; Lodola, Alessio
Amino acid conjugates of lithocholic acid as antagonists of the EphA2 receptor.
2013-01-01 Incerti, Matteo; Tognolini, Massimiliano; Russo, Simonetta; Pala, Daniele; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Noberini, R; Pasquale, Eb; Vicini, Paola; Piersanti, Silvia; Rivara, Silvia; Barocelli, Elisabetta; Mor, Marco; Lodola, Alessio
Atropisomerism and Conformational Equilibria: Impact on PI3Kδ Inhibition of 2-((6-Amino-9H-purin-9-yl)methyl)-5-methyl-3-(o-tolyl)quinazolin-4(3H)-one (IC87114) and Its Conformationally Restricted Analogs
2017-01-01 Lodola, Alessio; Bertolini, S; Biagetti, M; Capacchi, S; Facchinetti, F; Gallo, Pm; Pappani, A; Mor, Marco; Pala, Daniele; Rivara, Silvia; Visentini, F; Corsi, M; Capelli A., M.
Biochemical characterization of EphA2 antagonists with improved physico-chemical properties by cell-based assays and surface plasmon resonance analysis
2016-01-01 Giorgio, Carmine; Russo, Simonetta; Incerti, Matteo; Bugatti, Antonella; Vacondio, Federica; Barocelli, Elisabetta; Mor, Marco; Pala, Daniele; Hassan Mohamed, Iftiin; Gioiello, Antimo; Rusnati, Marco; Lodola, Alessio; Tognolini, Massimiliano
Combining ligand- and structure-based approaches for the discovery of new inhibitors of the EPHA2-ephrin-A1 interaction
2014-01-01 Pala, Daniele; Castelli, Riccardo; Incerti, Matteo; Russo, Simonetta; Tognolini, Massimiliano; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Zanotti, Ilaria; Vacondio, Federica; Rivara, Silvia; Mor, Marco; Lodola, Alessio
Combining pharmacology, target hopping and computational medicinal chemistry to discover novel scaffold targeting EPH-ephrin interaction.
2014-01-01 Tognolini, Massimiliano; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Castelli, Riccardo; Pala, Daniele; Mor, Marco; Barocelli, Elisabetta; Russo, Simonetta; Incerti, Matteo; Lodola, Alessio
Comparative Analysis of Virtual Screening Approaches in the Search for Novel EphA2 Receptor Antagonists
2015-01-01 Callegari, Donatella; Pala, Daniele; Scalvini, Laura; Tognolini, Massimiliano; Incerti, Matteo; Rivara, Silvia; Mor, Marco; Lodola, Alessio
Complex product composition generates risks for generic substitution also with dosage forms for intravenous administration
2013-01-01 Rossi, Alessandra; Buttini, Francesca; Colombo, Paolo; Mor, Marco; Pala, Daniele; F., Bortolotti; Colombo, Gaia
Computer-Aided Design of Novel Antagonists of the EphA2 Receptor
2013-01-01 Pala, Daniele; Rivara, Silvia; Incerti, Matteo; Tognolini, Massimiliano; Mor, Marco
Design and structure-activity relationship of amino acid derivatives of lithocholic acid as novel EphA2 antagonists
2012-01-01 Incerti, Matteo; Tognolini, Massimiliano; Russo, Simonetta; Pala, Daniele; HASSAN MOHAMED, Iftiin; Giorgio, Carmine; Vicini, Paola; Rivara, Silvia; Barocelli, Elisabetta; Mor, Marco; Lodola, Alessio
Design and structure-activity relationships of amino acid derivatives of lithocholic acid as novel EphA2 receptor antagonists.
2012-01-01 Incerti, Matteo; Tognolini, Massimiliano; Russo, Simonetta; Pala, Daniele; Iftiin Hassan Mohamed, ; Giorgio, Carmine; Vicini, Paola; Rivara, Silvia; Barocelli, Elisabetta; Mor, Marco; Lodola, Alessio
Development of 3-oxo-cholenic derivatives as Eph antagonists able to block in vitro angiogenesis
2014-01-01 HASSAN MOHAMED, Iftiin; Giorgio, Carmine; Castelli, Riccardo; Lodola, Alessio; Barocelli, Elisabetta; Mor, Marco; Russo, Simonetta; Incerti, Matteo; Pala, Daniele; Tognolini, Massimiliano
Development of an orally bioavailable small molecule targeting Eph-ephrin system: in vitro and in vivo anticancer activity.
2015-01-01 Tognolini, Massimiliano; Giorgio, Carmine; Festuccia, C; Rusnati, M; Chiodelli, P; Incerti, Matteo; Pala, Daniele; Callegari, Donatella; Bertoni, Simona; Castelli, Riccardo; Lodola, Alessio; Barocelli, Elisabetta
Dibasic biphenyl H(3) receptor antagonists: Steric tolerance for a lipophilic side chain.
2012-01-01 Bordi, Fabrizio; Rivara, Silvia; E., Dallaturca; Carmi, Caterina; Pala, Daniele; Lodola, Alessio; Vacondio, Federica; Flammini, Lisa; Bertoni, Simona; Ballabeni, Vigilio; Barocelli, Elisabetta; Mor, Marco
Discovery and development of Eph-ephrin antagonists endowed with antiangiogenic properties
2013-01-01 HASSAN MOHAMED, Iftiin; Giorgio, Carmine; Russo, Simonetta; Incerti, Matteo; Pala, Daniele; Lodola, Alessio; Barocelli, Elisabetta; Tognolini, Massimiliano
Discovery and development of low molecular weight Eph-ephrin protein-protein inhbi-tors endowed with antiangiogenic activity
2014-01-01 Tognolini, Massimiliano; HASSAN MOHAMED, Iftiin; Giorgio, Carmine; Incerti, Matteo; Barocelli, Elisabetta; Bertoni, Simona; Pala, Daniele; Mor, Marco; Russo, Simonetta; Lodola, Alessio
Exploiting Free-Energy Minima to Design Novel EphA2 Protein-Protein Antagonists: From Simulation to Experiment and Return
2016-01-01 Russo, Simonetta; Callegari, Donatella; Incerti, Matteo; Pala, Daniele; Giorgio, Carmine; Brunetti, Jlenia; Bracci, Luisa; Vicini, Paola; Barocelli, Elisabetta; Capoferri, Luigi; Rivara, Silvia; Tognolini, Massimiliano; Mor, Marco; Lodola, Alessio
Free-energy studies reveal a possible mechanism for oxidation-dependent inhibition of MGL
2016-01-01 Scalvini, Laura; Vacondio, Federica; Bassi, Michele; Pala, Daniele; Lodola, Alessio; Rivara, Silvia; Jung, Kwang Mook; Piomelli, Daniele; Mor, Marco
Highly Potent and Selective MT2 Melatonin Receptor Full Agonists from Conformational Analysis of 1-Benzyl-2-acylaminomethyl-tetrahydroquinolines
2015-01-01 Spadoni, Gilberto; Bedini, Annalida; Lucarini, Simone; Mari, Michele; Caignard, Daniel Henri; Boutin, Jean A.; Delagrange, Philippe; Lucini, Valeria; Scaglione, Francesco; Lodola, Alessio; Zanardi, Franca; Pala, Daniele; Mor, Marco; Rivara, Silvia
Homology models of melatonin receptors: challenges and recent advances.
2013-01-01 Pala, Daniele; Lodola, Alessio; Bedini, A.; Spadoni, G.; Rivara, Silvia
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 270 Discovery, development and optimization of low molecular weight EPH–ephrin protein–protein inhibitors | 1-gen-2014 | Tognolini, Massimiliano; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Barocelli, Elisabetta; Mor, Marco; Pala, Daniele; Russo, Simonetta; Incerti, Matteo; Lodola, Alessio | |
| Amino acid conjugates of lithocholic acid as antagonists of the EphA2 receptor. | 1-gen-2013 | Incerti, Matteo; Tognolini, Massimiliano; Russo, Simonetta; Pala, Daniele; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Noberini, R; Pasquale, Eb; Vicini, Paola; Piersanti, Silvia; Rivara, Silvia; Barocelli, Elisabetta; Mor, Marco; Lodola, Alessio | |
| Atropisomerism and Conformational Equilibria: Impact on PI3Kδ Inhibition of 2-((6-Amino-9H-purin-9-yl)methyl)-5-methyl-3-(o-tolyl)quinazolin-4(3H)-one (IC87114) and Its Conformationally Restricted Analogs | 1-gen-2017 | Lodola, Alessio; Bertolini, S; Biagetti, M; Capacchi, S; Facchinetti, F; Gallo, Pm; Pappani, A; Mor, Marco; Pala, Daniele; Rivara, Silvia; Visentini, F; Corsi, M; Capelli A., M. | |
| Biochemical characterization of EphA2 antagonists with improved physico-chemical properties by cell-based assays and surface plasmon resonance analysis | 1-gen-2016 | Giorgio, Carmine; Russo, Simonetta; Incerti, Matteo; Bugatti, Antonella; Vacondio, Federica; Barocelli, Elisabetta; Mor, Marco; Pala, Daniele; Hassan Mohamed, Iftiin; Gioiello, Antimo; Rusnati, Marco; Lodola, Alessio; Tognolini, Massimiliano | |
| Combining ligand- and structure-based approaches for the discovery of new inhibitors of the EPHA2-ephrin-A1 interaction | 1-gen-2014 | Pala, Daniele; Castelli, Riccardo; Incerti, Matteo; Russo, Simonetta; Tognolini, Massimiliano; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Zanotti, Ilaria; Vacondio, Federica; Rivara, Silvia; Mor, Marco; Lodola, Alessio | |
| Combining pharmacology, target hopping and computational medicinal chemistry to discover novel scaffold targeting EPH-ephrin interaction. | 1-gen-2014 | Tognolini, Massimiliano; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Castelli, Riccardo; Pala, Daniele; Mor, Marco; Barocelli, Elisabetta; Russo, Simonetta; Incerti, Matteo; Lodola, Alessio | |
| Comparative Analysis of Virtual Screening Approaches in the Search for Novel EphA2 Receptor Antagonists | 1-gen-2015 | Callegari, Donatella; Pala, Daniele; Scalvini, Laura; Tognolini, Massimiliano; Incerti, Matteo; Rivara, Silvia; Mor, Marco; Lodola, Alessio | |
| Complex product composition generates risks for generic substitution also with dosage forms for intravenous administration | 1-gen-2013 | Rossi, Alessandra; Buttini, Francesca; Colombo, Paolo; Mor, Marco; Pala, Daniele; F., Bortolotti; Colombo, Gaia | |
| Computer-Aided Design of Novel Antagonists of the EphA2 Receptor | 1-gen-2013 | Pala, Daniele; Rivara, Silvia; Incerti, Matteo; Tognolini, Massimiliano; Mor, Marco | |
| Design and structure-activity relationship of amino acid derivatives of lithocholic acid as novel EphA2 antagonists | 1-gen-2012 | Incerti, Matteo; Tognolini, Massimiliano; Russo, Simonetta; Pala, Daniele; HASSAN MOHAMED, Iftiin; Giorgio, Carmine; Vicini, Paola; Rivara, Silvia; Barocelli, Elisabetta; Mor, Marco; Lodola, Alessio | |
| Design and structure-activity relationships of amino acid derivatives of lithocholic acid as novel EphA2 receptor antagonists. | 1-gen-2012 | Incerti, Matteo; Tognolini, Massimiliano; Russo, Simonetta; Pala, Daniele; Iftiin Hassan Mohamed, ; Giorgio, Carmine; Vicini, Paola; Rivara, Silvia; Barocelli, Elisabetta; Mor, Marco; Lodola, Alessio | |
| Development of 3-oxo-cholenic derivatives as Eph antagonists able to block in vitro angiogenesis | 1-gen-2014 | HASSAN MOHAMED, Iftiin; Giorgio, Carmine; Castelli, Riccardo; Lodola, Alessio; Barocelli, Elisabetta; Mor, Marco; Russo, Simonetta; Incerti, Matteo; Pala, Daniele; Tognolini, Massimiliano | |
| Development of an orally bioavailable small molecule targeting Eph-ephrin system: in vitro and in vivo anticancer activity. | 1-gen-2015 | Tognolini, Massimiliano; Giorgio, Carmine; Festuccia, C; Rusnati, M; Chiodelli, P; Incerti, Matteo; Pala, Daniele; Callegari, Donatella; Bertoni, Simona; Castelli, Riccardo; Lodola, Alessio; Barocelli, Elisabetta | |
| Dibasic biphenyl H(3) receptor antagonists: Steric tolerance for a lipophilic side chain. | 1-gen-2012 | Bordi, Fabrizio; Rivara, Silvia; E., Dallaturca; Carmi, Caterina; Pala, Daniele; Lodola, Alessio; Vacondio, Federica; Flammini, Lisa; Bertoni, Simona; Ballabeni, Vigilio; Barocelli, Elisabetta; Mor, Marco | |
| Discovery and development of Eph-ephrin antagonists endowed with antiangiogenic properties | 1-gen-2013 | HASSAN MOHAMED, Iftiin; Giorgio, Carmine; Russo, Simonetta; Incerti, Matteo; Pala, Daniele; Lodola, Alessio; Barocelli, Elisabetta; Tognolini, Massimiliano | |
| Discovery and development of low molecular weight Eph-ephrin protein-protein inhbi-tors endowed with antiangiogenic activity | 1-gen-2014 | Tognolini, Massimiliano; HASSAN MOHAMED, Iftiin; Giorgio, Carmine; Incerti, Matteo; Barocelli, Elisabetta; Bertoni, Simona; Pala, Daniele; Mor, Marco; Russo, Simonetta; Lodola, Alessio | |
| Exploiting Free-Energy Minima to Design Novel EphA2 Protein-Protein Antagonists: From Simulation to Experiment and Return | 1-gen-2016 | Russo, Simonetta; Callegari, Donatella; Incerti, Matteo; Pala, Daniele; Giorgio, Carmine; Brunetti, Jlenia; Bracci, Luisa; Vicini, Paola; Barocelli, Elisabetta; Capoferri, Luigi; Rivara, Silvia; Tognolini, Massimiliano; Mor, Marco; Lodola, Alessio | |
| Free-energy studies reveal a possible mechanism for oxidation-dependent inhibition of MGL | 1-gen-2016 | Scalvini, Laura; Vacondio, Federica; Bassi, Michele; Pala, Daniele; Lodola, Alessio; Rivara, Silvia; Jung, Kwang Mook; Piomelli, Daniele; Mor, Marco | |
| Highly Potent and Selective MT2 Melatonin Receptor Full Agonists from Conformational Analysis of 1-Benzyl-2-acylaminomethyl-tetrahydroquinolines | 1-gen-2015 | Spadoni, Gilberto; Bedini, Annalida; Lucarini, Simone; Mari, Michele; Caignard, Daniel Henri; Boutin, Jean A.; Delagrange, Philippe; Lucini, Valeria; Scaglione, Francesco; Lodola, Alessio; Zanardi, Franca; Pala, Daniele; Mor, Marco; Rivara, Silvia | |
| Homology models of melatonin receptors: challenges and recent advances. | 1-gen-2013 | Pala, Daniele; Lodola, Alessio; Bedini, A.; Spadoni, G.; Rivara, Silvia |