GIORGIO, Carmine
GIORGIO, Carmine
Dipartimento di Scienze degli Alimenti e del Farmaco
1,8-Naphthyridines IX. Potent anti-inflammatory and/or analgesic activity of a new group of substituted 5 amino[1,2,4]triazolo[4,3-a] [1,8]naphthyridine-6 carboxamides, of some their Mannich base derivatives and of one novel substituted 5-amino-10-oxo-10Hpyrimido[1,2-a [1,8]naphthyridine-6-carboxamide derivative
2014-01-01 M., Di Braccio; G., Grossi; S., Alfei; Ballabeni, Vigilio; Tognolini, Massimiliano; Flammini, Lisa; Giorgio, Carmine; Bertoni, Simona; Barocelli, Elisabetta
1-Methyl and 1-(2-hydroxyalkyl)-5-(3-alkyl/cycloalkyl/phenyl/naphthylureido)-1H-pyrazole-4-carboxylic acid ethyl esters as potent human neutrophil chemotaxis inhibitors
2009-01-01 Bruno, O.; Brullo, C.; Bondavalli, F.; Schenone, S.; Spisani, S.; Falzarano, M. S.; Varani, K.; Barocelli, Elisabetta; Ballabeni, Vigilio; Giorgio, Carmine; Tognolini, Massimiliano
270 Discovery, development and optimization of low molecular weight EPH–ephrin protein–protein inhibitors
2014-01-01 Tognolini, Massimiliano; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Barocelli, Elisabetta; Mor, Marco; Pala, Daniele; Russo, Simonetta; Incerti, Matteo; Lodola, Alessio
A Pharmacological Investigation of Eph-Ephrin Antagonism in Prostate Cancer: UniPR1331 Efficacy Evidence
2023-01-01 Festuccia, Claudio; Corrado, Miriam; Rossetti, Alessandra; Castelli, Riccardo; Lodola, Alessio; Gravina, Giovanni Luca; Tognolini, Massimiliano; Giorgio, Carmine
Amino acid conjugates of lithocholic acid as antagonists of the EphA2 receptor.
2013-01-01 Incerti, Matteo; Tognolini, Massimiliano; Russo, Simonetta; Pala, Daniele; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Noberini, R; Pasquale, Eb; Vicini, Paola; Piersanti, Silvia; Rivara, Silvia; Barocelli, Elisabetta; Mor, Marco; Lodola, Alessio
Antinflammatory properties of novel 5-amino[1,2,4]-triazolo[4,3-a][1,8]naphthyridines-caroboxamides derivatives
2009-01-01 Giorgio, Carmine; Tognolini, Massimiliano; Roma, Giorgio; DI BRACCIO, Mario; Ballabeni, Vigilio; Barocelli, Elisabetta
Biochemical characterization of EphA2 antagonists with improved physico-chemical properties by cell-based assays and surface plasmon resonance analysis
2016-01-01 Giorgio, Carmine; Russo, Simonetta; Incerti, Matteo; Bugatti, Antonella; Vacondio, Federica; Barocelli, Elisabetta; Mor, Marco; Pala, Daniele; Hassan Mohamed, Iftiin; Gioiello, Antimo; Rusnati, Marco; Lodola, Alessio; Tognolini, Massimiliano
Botanicals used as food supplements interfering with EphA2-ephrinA1 system: a screening study
2011-01-01 Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Bruni, Renato; Flammini, Lisa; Barocelli, Elisabetta; A., Guerrini; Bertoni, Simona; Tognolini, Massimiliano
Combining ligand- and structure-based approaches for the discovery of new inhibitors of the EPHA2-ephrin-A1 interaction
2014-01-01 Pala, Daniele; Castelli, Riccardo; Incerti, Matteo; Russo, Simonetta; Tognolini, Massimiliano; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Zanotti, Ilaria; Vacondio, Federica; Rivara, Silvia; Mor, Marco; Lodola, Alessio
Combining pharmacology, target hopping and computational medicinal chemistry to discover novel scaffold targeting EPH-ephrin interaction.
2014-01-01 Tognolini, Massimiliano; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Castelli, Riccardo; Pala, Daniele; Mor, Marco; Barocelli, Elisabetta; Russo, Simonetta; Incerti, Matteo; Lodola, Alessio
Design and structure-activity relationship of amino acid derivatives of lithocholic acid as novel EphA2 antagonists
2012-01-01 Incerti, Matteo; Tognolini, Massimiliano; Russo, Simonetta; Pala, Daniele; HASSAN MOHAMED, Iftiin; Giorgio, Carmine; Vicini, Paola; Rivara, Silvia; Barocelli, Elisabetta; Mor, Marco; Lodola, Alessio
Design and structure-activity relationships of amino acid derivatives of lithocholic acid as novel EphA2 receptor antagonists.
2012-01-01 Incerti, Matteo; Tognolini, Massimiliano; Russo, Simonetta; Pala, Daniele; Iftiin Hassan Mohamed, ; Giorgio, Carmine; Vicini, Paola; Rivara, Silvia; Barocelli, Elisabetta; Mor, Marco; Lodola, Alessio
Development of 3-oxo-cholenic derivatives as Eph antagonists able to block in vitro angiogenesis
2014-01-01 HASSAN MOHAMED, Iftiin; Giorgio, Carmine; Castelli, Riccardo; Lodola, Alessio; Barocelli, Elisabetta; Mor, Marco; Russo, Simonetta; Incerti, Matteo; Pala, Daniele; Tognolini, Massimiliano
Development of an orally bioavailable small molecule targeting Eph-ephrin system: in vitro and in vivo anticancer activity.
2015-01-01 Tognolini, Massimiliano; Giorgio, Carmine; Festuccia, C; Rusnati, M; Chiodelli, P; Incerti, Matteo; Pala, Daniele; Callegari, Donatella; Bertoni, Simona; Castelli, Riccardo; Lodola, Alessio; Barocelli, Elisabetta
Discovery and development of Eph-ephrin antagonists endowed with antiangiogenic properties
2013-01-01 HASSAN MOHAMED, Iftiin; Giorgio, Carmine; Russo, Simonetta; Incerti, Matteo; Pala, Daniele; Lodola, Alessio; Barocelli, Elisabetta; Tognolini, Massimiliano
Discovery and development of low molecular weight Eph-ephrin protein-protein inhbi-tors endowed with antiangiogenic activity
2014-01-01 Tognolini, Massimiliano; HASSAN MOHAMED, Iftiin; Giorgio, Carmine; Incerti, Matteo; Barocelli, Elisabetta; Bertoni, Simona; Pala, Daniele; Mor, Marco; Russo, Simonetta; Lodola, Alessio
Discovery and development of small molecules targeting Eph-ephrin system in glioblastoma: an academic history
2017-01-01 Tognolini, Massimiliano; Claudio, Festuccia; Gianluca, Gravina; Castelli, Riccardo; Incerti, Matteo; Vacondio, Federica; Callegari, Donatella; Simonetta, Russo; Barocelli, Elisabetta; Marco, Rusnati; Paola, Chiodelli; Lodola, Alessio; Giorgio, Carmine
Discovery of natural extracts interfering with EphA2-ephrinA1 system
2010-01-01 Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Bruni, Renato; Domenichini, Giuseppe; Barocelli, Elisabetta; Tognolini, Massimiliano
Discovery of small-molecule targeting the CCL20/CCR6 axis as first-in-class inhibitors for inflammatory bowel diseases
2022-01-01 Martina, MARIA GRAZIA; Giorgio, Carmine; Allodi, Marika; Palese, Simone; Barocelli, Elisabetta; Ballabeni, Vigilio; Szpakowska, Martyna; Chevigné, Andy; Piet van Hamburg, Jan; Davelaar, Nadine; Lubberts, Erik; Bertoni, Simona; Radi, Marco
Drug discovery: In silico dry data can bypass biological wet data?
2023-01-01 Tognolini, Massimiliano; Lodola, Alessio; Giorgio, Carmine
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 1,8-Naphthyridines IX. Potent anti-inflammatory and/or analgesic activity of a new group of substituted 5 amino[1,2,4]triazolo[4,3-a] [1,8]naphthyridine-6 carboxamides, of some their Mannich base derivatives and of one novel substituted 5-amino-10-oxo-10Hpyrimido[1,2-a [1,8]naphthyridine-6-carboxamide derivative | 1-gen-2014 | M., Di Braccio; G., Grossi; S., Alfei; Ballabeni, Vigilio; Tognolini, Massimiliano; Flammini, Lisa; Giorgio, Carmine; Bertoni, Simona; Barocelli, Elisabetta | |
| 1-Methyl and 1-(2-hydroxyalkyl)-5-(3-alkyl/cycloalkyl/phenyl/naphthylureido)-1H-pyrazole-4-carboxylic acid ethyl esters as potent human neutrophil chemotaxis inhibitors | 1-gen-2009 | Bruno, O.; Brullo, C.; Bondavalli, F.; Schenone, S.; Spisani, S.; Falzarano, M. S.; Varani, K.; Barocelli, Elisabetta; Ballabeni, Vigilio; Giorgio, Carmine; Tognolini, Massimiliano | |
| 270 Discovery, development and optimization of low molecular weight EPH–ephrin protein–protein inhibitors | 1-gen-2014 | Tognolini, Massimiliano; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Barocelli, Elisabetta; Mor, Marco; Pala, Daniele; Russo, Simonetta; Incerti, Matteo; Lodola, Alessio | |
| A Pharmacological Investigation of Eph-Ephrin Antagonism in Prostate Cancer: UniPR1331 Efficacy Evidence | 1-gen-2023 | Festuccia, Claudio; Corrado, Miriam; Rossetti, Alessandra; Castelli, Riccardo; Lodola, Alessio; Gravina, Giovanni Luca; Tognolini, Massimiliano; Giorgio, Carmine | |
| Amino acid conjugates of lithocholic acid as antagonists of the EphA2 receptor. | 1-gen-2013 | Incerti, Matteo; Tognolini, Massimiliano; Russo, Simonetta; Pala, Daniele; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Noberini, R; Pasquale, Eb; Vicini, Paola; Piersanti, Silvia; Rivara, Silvia; Barocelli, Elisabetta; Mor, Marco; Lodola, Alessio | |
| Antinflammatory properties of novel 5-amino[1,2,4]-triazolo[4,3-a][1,8]naphthyridines-caroboxamides derivatives | 1-gen-2009 | Giorgio, Carmine; Tognolini, Massimiliano; Roma, Giorgio; DI BRACCIO, Mario; Ballabeni, Vigilio; Barocelli, Elisabetta | |
| Biochemical characterization of EphA2 antagonists with improved physico-chemical properties by cell-based assays and surface plasmon resonance analysis | 1-gen-2016 | Giorgio, Carmine; Russo, Simonetta; Incerti, Matteo; Bugatti, Antonella; Vacondio, Federica; Barocelli, Elisabetta; Mor, Marco; Pala, Daniele; Hassan Mohamed, Iftiin; Gioiello, Antimo; Rusnati, Marco; Lodola, Alessio; Tognolini, Massimiliano | |
| Botanicals used as food supplements interfering with EphA2-ephrinA1 system: a screening study | 1-gen-2011 | Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Bruni, Renato; Flammini, Lisa; Barocelli, Elisabetta; A., Guerrini; Bertoni, Simona; Tognolini, Massimiliano | |
| Combining ligand- and structure-based approaches for the discovery of new inhibitors of the EPHA2-ephrin-A1 interaction | 1-gen-2014 | Pala, Daniele; Castelli, Riccardo; Incerti, Matteo; Russo, Simonetta; Tognolini, Massimiliano; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Zanotti, Ilaria; Vacondio, Federica; Rivara, Silvia; Mor, Marco; Lodola, Alessio | |
| Combining pharmacology, target hopping and computational medicinal chemistry to discover novel scaffold targeting EPH-ephrin interaction. | 1-gen-2014 | Tognolini, Massimiliano; Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Castelli, Riccardo; Pala, Daniele; Mor, Marco; Barocelli, Elisabetta; Russo, Simonetta; Incerti, Matteo; Lodola, Alessio | |
| Design and structure-activity relationship of amino acid derivatives of lithocholic acid as novel EphA2 antagonists | 1-gen-2012 | Incerti, Matteo; Tognolini, Massimiliano; Russo, Simonetta; Pala, Daniele; HASSAN MOHAMED, Iftiin; Giorgio, Carmine; Vicini, Paola; Rivara, Silvia; Barocelli, Elisabetta; Mor, Marco; Lodola, Alessio | |
| Design and structure-activity relationships of amino acid derivatives of lithocholic acid as novel EphA2 receptor antagonists. | 1-gen-2012 | Incerti, Matteo; Tognolini, Massimiliano; Russo, Simonetta; Pala, Daniele; Iftiin Hassan Mohamed, ; Giorgio, Carmine; Vicini, Paola; Rivara, Silvia; Barocelli, Elisabetta; Mor, Marco; Lodola, Alessio | |
| Development of 3-oxo-cholenic derivatives as Eph antagonists able to block in vitro angiogenesis | 1-gen-2014 | HASSAN MOHAMED, Iftiin; Giorgio, Carmine; Castelli, Riccardo; Lodola, Alessio; Barocelli, Elisabetta; Mor, Marco; Russo, Simonetta; Incerti, Matteo; Pala, Daniele; Tognolini, Massimiliano | |
| Development of an orally bioavailable small molecule targeting Eph-ephrin system: in vitro and in vivo anticancer activity. | 1-gen-2015 | Tognolini, Massimiliano; Giorgio, Carmine; Festuccia, C; Rusnati, M; Chiodelli, P; Incerti, Matteo; Pala, Daniele; Callegari, Donatella; Bertoni, Simona; Castelli, Riccardo; Lodola, Alessio; Barocelli, Elisabetta | |
| Discovery and development of Eph-ephrin antagonists endowed with antiangiogenic properties | 1-gen-2013 | HASSAN MOHAMED, Iftiin; Giorgio, Carmine; Russo, Simonetta; Incerti, Matteo; Pala, Daniele; Lodola, Alessio; Barocelli, Elisabetta; Tognolini, Massimiliano | |
| Discovery and development of low molecular weight Eph-ephrin protein-protein inhbi-tors endowed with antiangiogenic activity | 1-gen-2014 | Tognolini, Massimiliano; HASSAN MOHAMED, Iftiin; Giorgio, Carmine; Incerti, Matteo; Barocelli, Elisabetta; Bertoni, Simona; Pala, Daniele; Mor, Marco; Russo, Simonetta; Lodola, Alessio | |
| Discovery and development of small molecules targeting Eph-ephrin system in glioblastoma: an academic history | 1-gen-2017 | Tognolini, Massimiliano; Claudio, Festuccia; Gianluca, Gravina; Castelli, Riccardo; Incerti, Matteo; Vacondio, Federica; Callegari, Donatella; Simonetta, Russo; Barocelli, Elisabetta; Marco, Rusnati; Paola, Chiodelli; Lodola, Alessio; Giorgio, Carmine | |
| Discovery of natural extracts interfering with EphA2-ephrinA1 system | 1-gen-2010 | Giorgio, Carmine; HASSAN MOHAMED, Iftiin; Bruni, Renato; Domenichini, Giuseppe; Barocelli, Elisabetta; Tognolini, Massimiliano | |
| Discovery of small-molecule targeting the CCL20/CCR6 axis as first-in-class inhibitors for inflammatory bowel diseases | 1-gen-2022 | Martina, MARIA GRAZIA; Giorgio, Carmine; Allodi, Marika; Palese, Simone; Barocelli, Elisabetta; Ballabeni, Vigilio; Szpakowska, Martyna; Chevigné, Andy; Piet van Hamburg, Jan; Davelaar, Nadine; Lubberts, Erik; Bertoni, Simona; Radi, Marco | |
| Drug discovery: In silico dry data can bypass biological wet data? | 1-gen-2023 | Tognolini, Massimiliano; Lodola, Alessio; Giorgio, Carmine |