This thesis focuses on the design and synthesis of multifunctional materials for two main purposes: biomarker recognition and self-healing/self-diagnostic applications. Materials are defined as functional when they can perform a specific function in response to a stimulus and they include nanoparticles, polymers, and others. This work is divided into two parts. The first part investigates the use of functionalized iron nanoparticles with supramolecular receptors for the detection of biomarkers, in particular modifications of histones and RNA. The second part deals with the synthesis of dynamic networks with self-diagnostic properties, aiming to extend the lifespan of materials within the context of a circular economy.

Design and Development of Multifunctional Materials for Biomarker Recognition and Self-Healing/Self-Diagnostic Applications / Nicolella Gentile, R.. - (2026).

Design and Development of Multifunctional Materials for Biomarker Recognition and Self-Healing/Self-Diagnostic Applications

NICOLELLA GENTILE, ROSITA
2026-01-01

Abstract

This thesis focuses on the design and synthesis of multifunctional materials for two main purposes: biomarker recognition and self-healing/self-diagnostic applications. Materials are defined as functional when they can perform a specific function in response to a stimulus and they include nanoparticles, polymers, and others. This work is divided into two parts. The first part investigates the use of functionalized iron nanoparticles with supramolecular receptors for the detection of biomarkers, in particular modifications of histones and RNA. The second part deals with the synthesis of dynamic networks with self-diagnostic properties, aiming to extend the lifespan of materials within the context of a circular economy.
2026
Scienze e Tecnologie dei Materiali
Biomarkers
Post-traslational modifications
Covalent adaptable networks
supramolecular chemistry
Polymer chemistry
Epitranscriptomic
Self-diagnostic polymers
Epigenetic
Mechanochromophores
Molecular receptors
Mechanophores
PINALLI, Roberta
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/1889/6583
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