Recent Advances on the Synthesis of [4.3.0] Bicycles Featuring Three Heteroatoms Including a Bridgehead One

The manuscript details all of the relevant recent reports on the assembly of fused [4.3.0] bicycles incorporating three heteroatoms, among which one occupies a bridgehead position. Several elegant strategies have been developed as well as the application of known routes enabled a concise access to these highly functionalized scaffolds. This work presents all of these advances ordered on the basis of the structure of the desired heterocycles. Each subsection features both stoichiometric and catalytic synthetic strategies that were applied to the assembly of these compelling targets