2AbstractBackgroundThe increasing use of cadmium sulphide (CdS) quantum dot (QD)-enabled products is expected to be accompanied by their release into the environment. In this study, the whole organism Saccharomyces cerevisiae was used as a model eukaryote to study protein modulations employing 2D- gel-electrophoresis and gel-free iTRAQ (Isobaric Tags for Relative and Absolute Quantitation) proteomics following cell exposure to CdS QDs for 9 and 24 h. From both biotechnological and ecotoxicological perspectives, the use of S. cerevisiae a model organism sheds light on the impact nanomaterials has on the biochemical responses of the exposed organism.

Proteomic analysis to identify markers of exposure to cadmium sulphide quantum dots (CdS QDs) / Gallo, Valentina; Srivast, Vaibhav; Bulone, Vincent; Zappettini, Andrea; Villani, Marco; Marmiroli, Nelson; Marmiroli, Marta. - In: NANOMATERIALS. - ISSN 2079-4991. - (2020). [10.21203/rs.2.22437/v1]

Proteomic analysis to identify markers of exposure to cadmium sulphide quantum dots (CdS QDs)

Gallo, Valentina;Villani, Marco;Marmiroli, Nelson;Marmiroli, Marta
2020-01-01

Abstract

2AbstractBackgroundThe increasing use of cadmium sulphide (CdS) quantum dot (QD)-enabled products is expected to be accompanied by their release into the environment. In this study, the whole organism Saccharomyces cerevisiae was used as a model eukaryote to study protein modulations employing 2D- gel-electrophoresis and gel-free iTRAQ (Isobaric Tags for Relative and Absolute Quantitation) proteomics following cell exposure to CdS QDs for 9 and 24 h. From both biotechnological and ecotoxicological perspectives, the use of S. cerevisiae a model organism sheds light on the impact nanomaterials has on the biochemical responses of the exposed organism.
Proteomic analysis to identify markers of exposure to cadmium sulphide quantum dots (CdS QDs) / Gallo, Valentina; Srivast, Vaibhav; Bulone, Vincent; Zappettini, Andrea; Villani, Marco; Marmiroli, Nelson; Marmiroli, Marta. - In: NANOMATERIALS. - ISSN 2079-4991. - (2020). [10.21203/rs.2.22437/v1]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2878838
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