DIGIACOMO, GRAZIANA
DIGIACOMO, GRAZIANA
Dipartimento di Medicina e Chirurgia
Acquired BRAF G469A Mutation as a Resistance Mechanism to First-Line Osimertinib Treatment in NSCLC Cell Lines Harboring an EGFR Exon 19 Deletion
2019-01-01 La Monica, S.; Minari, R.; Cretella, D.; Bonelli, M.; Fumarola, C.; Cavazzoni, A.; Galetti, M.; Digiacomo, G.; Riccardi, F.; Petronini, P. G.; Tiseo, M.; Alfieri, R.
Balancing reactivity and antitumor activity: heteroarylthioacetamide derivatives as potent and time-dependent inhibitors of EGFR
2019-01-01 Castelli, R; Bozza, N; Cavazzoni, A; Bonelli, M; Vacondio, F; Ferlenghi, F; Callegari, D; Silva, C; Rivara, S; Lodola, A; Digiacomo, G; Fumarola, C; Alfieri, R; Petronini, Pg; Mor, M.
Biological hallmarks and new therapeutic approaches for the treatment of pdac
2021-01-01 Digiacomo, G.; Volta, F.; Garajova, I.; Balsano, R.; Cavazzoni, A.
CDK4/6 Inhibition Enhances the Efficacy of Standard Chemotherapy Treatment in Malignant Pleural Mesothelioma Cells
2022-01-01 Terenziani, Rita; Galetti, Maricla; La Monica, Silvia; Fumarola, Claudia; Zoppi, Silvia; Alfieri, Roberta; Digiacomo, Graziana; Cavazzoni, Andrea; Cavallo, Delia; Corradi, Massimo; Tiseo, Marcello; Petronini, Pier Giorgio; Bonelli, Mara
CDK4/6 inhibitors improve the anti-tumor efficacy of lenvatinib in hepatocarcinoma cells
2022-01-01 Digiacomo, Graziana; Fumarola, Claudia; La Monica, Silvia; Bonelli, Mara; Cavazzoni, Andrea; Galetti, Maricla; Terenziani, Rita; Eltayeb, Kamal; Volta, Francesco; Zoppi, Silvia; Bertolini, Patrizia; Missale, Gabriele; Alfieri, Roberta; Petronini, Pier Giorgio
Chromatin-associated CSF-1R binds to the promoter of proliferation-related genes in breast cancer cells
2014-01-01 Barbetti, V.; Morandi, A.; Tusa, I.; Digiacomo, Graziana; Riverso, M.; Marzi, I.; Cipolleschi, M. G.; Bessi, S.; Giannini, A.; Di Leo, A.; Dello Sbarba, P.; Rovida, E.
Circulating TGF-Beta and PD-L1 in Pancreatic Cancer
2022-01-01 Garajova, Ingrid; Cavazzoni, Andrea; Verze, Michela; Minari, Roberta; Pedrazzi, Giuseppe; Balsano, Rita; Digiacomo, Graziana; Leonardi, Francesco
Combined Inhibition of CDK4/6 and PI3K/AKT/mTOR Pathways Induces a Synergistic Anti-Tumor Effect in Malignant Pleural Mesothelioma Cells.
2017-01-01 Bonelli, Mara; Digiacomo, Graziana; Fumarola, Claudia; Alfieri, Roberta; Quaini, Federico; Falco, Angela; Madeddu, Denise; LA MONICA, Silvia; Cretella, Daniele; Ravelli, Andrea; Ulivi, P; Tebaldi, M; Calistri, D; Delmonte, A; Ampollini, Luca; Carbognani, Paolo; Tiseo, Marcello; Cavazzoni, Andrea; Petronini, Pier Giorgio
Dual inhibition of CDK4/6 and PI3K/AKT/mTOR signaling impairs energy metabolism in MPM cancer cells
2020-01-01 Bonelli, M.; Terenziani, R.; Zoppi, S.; Fumarola, C.; La Monica, S.; Cretella, D.; Alfieri, R.; Cavazzoni, A.; Digiacomo, G.; Galetti, M.; Petronini, P. G.
Efficacy of the cdk4/6 dual inhibitor abemaciclib in egfr-mutated nsclc cell lines with different resistance mechanisms to osimertinib
2021-01-01 LA Monica, S.; Fumarola, C.; Cretella, D.; Bonelli, M.; Minari, R.; Cavazzoni, A.; Digiacomo, G.; Galetti, M.; Volta, F.; Mancini, M.; Petronini, P. G.; Tiseo, M.; Alfieri, R.
Enhanced efficacy of AKT and FAK kinase combined inhibition in squamous cell lung carcinomas with stable reduction in PTEN
2017-01-01 Cavazzoni, Andrea; La Monica, Silvia; Alfieri, Roberta; Ravelli, Andrea; Steen, Nele Van Der; Sciarrillo, Rocco; Madeddu, Denise; Lagrasta, Costanza Anna Maria; Quaini, Federico; Bonelli, Mara; Fumarola, Claudia; Cretella, Daniele; Digiacomo, Graziana; Tiseo, Marcello; Peters, Godefridus J.; Ardizzoni, Andrea; Petronini, Pier Giorgio; and Elisa, Giovannetti
Enhancement of the anti-tumor activity of FGFR1 inhibition in squamous cell lung cancer by targeting downstream signaling involved in glucose metabolism.
2017-01-01 Fumarola, Claudia; Cretella, Daniele; LA MONICA, Silvia; Bonelli, Mara; Alfieri, Roberta; Caffarra, Cristina; Quaini, Federico; Madeddu, Denise; Falco, Angela; Cavazzoni, Andrea; Digiacomo, Graziana; Mazzaschi, Giulia; Vivo, Valentina; Barocelli, Elisabetta; Tiseo, Marcello; Petronini, Pier Giorgio; Ardizzoni, Andrea
Fibronectin induces macrophage migration through a SFK-FAK/CSF-1R pathway
2017-01-01 Digiacomo, Graziana; Tusa, Ignazia; Bacci, Marina; Cipolleschi, Maria Grazia; Dello Sbarba, Persio; Rovida, Elisabetta
INCREASED SOLUBLE AND MEMBRANE-BOUND PD-L1 EXPRESSION IN NSCLC CELL LINES TREATED WITH PEMETREXED
2018-01-01 Cavazzoni, A.; Digiacomo, G.; Petronini, P. G.; Fiorentino, M.; Ardizzoni, A.; Alfieri, R.
It Takes Two to Tango: Potential Prognostic Impact of Circulating TGF-Beta and PD-L1 in Pancreatic Cancer
2022-01-01 Garajová, Ingrid; Cavazzoni, Andrea; Verze, Michela; Minari, Roberta; Pedrazzi, Giuseppe; Balsano, Rita; Gelsomino, Fabio; DALLA VALLE, Raffaele; Digiacomo, Graziana; Giovannetti, Elisa; Leonardi, Francesco
Overcoming Palbociclib Resistance by Combined Treatment with PI3K/AKT/mTOR Inhibitors in Mesothelioma Cells
2018-01-01 Digiacomo, Graziana; Fumarola, Claudia; Cretella, Daniele; Alfieri, Roberta; LA MONICA, Silvia; Petronini, Pier Giorgio; Bonelli, Mara; Cavazzoni, Andrea
PD-L1 level is up-regulated in NSCLC cells after pemetrexed treatment
2018-01-01 Cavazzoni, A.; Digiacomo, G.; La Monica, S.; Alfieri, R.; Fiorentino, M.; Ardizzoni, A.; Petronini, Pg.
PD-L1 OVEREXPRESSION INDUCES ANGIOGENIC CYTOKINE SECRETION AND ENDOTHELIAL CELL MIGRATION VIA STAT SIGNALLING.
2023-01-01 Digiacomo, G.; Cavazzoni, A.; Volta, F.; Alfieri, R.; Petronini, P. G.; Tiseo, M.
PD-L1 overexpression induces STAT signaling and promotes the secretion of pro-angiogenic cytokines in non-small cell lung cancer (NSCLC)
2024-01-01 Cavazzoni, A.; Digiacomo, G.; Volta, F.; Alfieri, R.; Giovannetti, E.; Gnetti, L.; Bellini, L.; Galetti, M.; Fumarola, C.; Xu, G.; Bonelli, M.; La Monica, S.; Verze, M.; Leonetti, A.; Eltayeb, K.; D'Agnelli, S.; Moron Dalla Tor, L.; Minari, R.; Petronini, P. G.; Tiseo, M.
Pemetrexed enhances membrane PD-L1 expression and potentiates T cell-mediated cytotoxicity by anti-PD-L1 antibody therapy in non-small-cell lung cancer
2020-01-01 Cavazzoni, A.; Digiacomo, G.; Alfieri, R.; La Monica, S.; Fumarola, C.; Galetti, M.; Bonelli, M.; Cretella, D.; Barili, V.; Zecca, A.; Giovannetti, E.; Fiorentino, M.; Tiseo, M.; Petronini, P. G.; Ardizzoni, A.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Acquired BRAF G469A Mutation as a Resistance Mechanism to First-Line Osimertinib Treatment in NSCLC Cell Lines Harboring an EGFR Exon 19 Deletion | 1-gen-2019 | La Monica, S.; Minari, R.; Cretella, D.; Bonelli, M.; Fumarola, C.; Cavazzoni, A.; Galetti, M.; Digiacomo, G.; Riccardi, F.; Petronini, P. G.; Tiseo, M.; Alfieri, R. | |
| Balancing reactivity and antitumor activity: heteroarylthioacetamide derivatives as potent and time-dependent inhibitors of EGFR | 1-gen-2019 | Castelli, R; Bozza, N; Cavazzoni, A; Bonelli, M; Vacondio, F; Ferlenghi, F; Callegari, D; Silva, C; Rivara, S; Lodola, A; Digiacomo, G; Fumarola, C; Alfieri, R; Petronini, Pg; Mor, M. | |
| Biological hallmarks and new therapeutic approaches for the treatment of pdac | 1-gen-2021 | Digiacomo, G.; Volta, F.; Garajova, I.; Balsano, R.; Cavazzoni, A. | |
| CDK4/6 Inhibition Enhances the Efficacy of Standard Chemotherapy Treatment in Malignant Pleural Mesothelioma Cells | 1-gen-2022 | Terenziani, Rita; Galetti, Maricla; La Monica, Silvia; Fumarola, Claudia; Zoppi, Silvia; Alfieri, Roberta; Digiacomo, Graziana; Cavazzoni, Andrea; Cavallo, Delia; Corradi, Massimo; Tiseo, Marcello; Petronini, Pier Giorgio; Bonelli, Mara | |
| CDK4/6 inhibitors improve the anti-tumor efficacy of lenvatinib in hepatocarcinoma cells | 1-gen-2022 | Digiacomo, Graziana; Fumarola, Claudia; La Monica, Silvia; Bonelli, Mara; Cavazzoni, Andrea; Galetti, Maricla; Terenziani, Rita; Eltayeb, Kamal; Volta, Francesco; Zoppi, Silvia; Bertolini, Patrizia; Missale, Gabriele; Alfieri, Roberta; Petronini, Pier Giorgio | |
| Chromatin-associated CSF-1R binds to the promoter of proliferation-related genes in breast cancer cells | 1-gen-2014 | Barbetti, V.; Morandi, A.; Tusa, I.; Digiacomo, Graziana; Riverso, M.; Marzi, I.; Cipolleschi, M. G.; Bessi, S.; Giannini, A.; Di Leo, A.; Dello Sbarba, P.; Rovida, E. | |
| Circulating TGF-Beta and PD-L1 in Pancreatic Cancer | 1-gen-2022 | Garajova, Ingrid; Cavazzoni, Andrea; Verze, Michela; Minari, Roberta; Pedrazzi, Giuseppe; Balsano, Rita; Digiacomo, Graziana; Leonardi, Francesco | |
| Combined Inhibition of CDK4/6 and PI3K/AKT/mTOR Pathways Induces a Synergistic Anti-Tumor Effect in Malignant Pleural Mesothelioma Cells. | 1-gen-2017 | Bonelli, Mara; Digiacomo, Graziana; Fumarola, Claudia; Alfieri, Roberta; Quaini, Federico; Falco, Angela; Madeddu, Denise; LA MONICA, Silvia; Cretella, Daniele; Ravelli, Andrea; Ulivi, P; Tebaldi, M; Calistri, D; Delmonte, A; Ampollini, Luca; Carbognani, Paolo; Tiseo, Marcello; Cavazzoni, Andrea; Petronini, Pier Giorgio | |
| Dual inhibition of CDK4/6 and PI3K/AKT/mTOR signaling impairs energy metabolism in MPM cancer cells | 1-gen-2020 | Bonelli, M.; Terenziani, R.; Zoppi, S.; Fumarola, C.; La Monica, S.; Cretella, D.; Alfieri, R.; Cavazzoni, A.; Digiacomo, G.; Galetti, M.; Petronini, P. G. | |
| Efficacy of the cdk4/6 dual inhibitor abemaciclib in egfr-mutated nsclc cell lines with different resistance mechanisms to osimertinib | 1-gen-2021 | LA Monica, S.; Fumarola, C.; Cretella, D.; Bonelli, M.; Minari, R.; Cavazzoni, A.; Digiacomo, G.; Galetti, M.; Volta, F.; Mancini, M.; Petronini, P. G.; Tiseo, M.; Alfieri, R. | |
| Enhanced efficacy of AKT and FAK kinase combined inhibition in squamous cell lung carcinomas with stable reduction in PTEN | 1-gen-2017 | Cavazzoni, Andrea; La Monica, Silvia; Alfieri, Roberta; Ravelli, Andrea; Steen, Nele Van Der; Sciarrillo, Rocco; Madeddu, Denise; Lagrasta, Costanza Anna Maria; Quaini, Federico; Bonelli, Mara; Fumarola, Claudia; Cretella, Daniele; Digiacomo, Graziana; Tiseo, Marcello; Peters, Godefridus J.; Ardizzoni, Andrea; Petronini, Pier Giorgio; and Elisa, Giovannetti | |
| Enhancement of the anti-tumor activity of FGFR1 inhibition in squamous cell lung cancer by targeting downstream signaling involved in glucose metabolism. | 1-gen-2017 | Fumarola, Claudia; Cretella, Daniele; LA MONICA, Silvia; Bonelli, Mara; Alfieri, Roberta; Caffarra, Cristina; Quaini, Federico; Madeddu, Denise; Falco, Angela; Cavazzoni, Andrea; Digiacomo, Graziana; Mazzaschi, Giulia; Vivo, Valentina; Barocelli, Elisabetta; Tiseo, Marcello; Petronini, Pier Giorgio; Ardizzoni, Andrea | |
| Fibronectin induces macrophage migration through a SFK-FAK/CSF-1R pathway | 1-gen-2017 | Digiacomo, Graziana; Tusa, Ignazia; Bacci, Marina; Cipolleschi, Maria Grazia; Dello Sbarba, Persio; Rovida, Elisabetta | |
| INCREASED SOLUBLE AND MEMBRANE-BOUND PD-L1 EXPRESSION IN NSCLC CELL LINES TREATED WITH PEMETREXED | 1-gen-2018 | Cavazzoni, A.; Digiacomo, G.; Petronini, P. G.; Fiorentino, M.; Ardizzoni, A.; Alfieri, R. | |
| It Takes Two to Tango: Potential Prognostic Impact of Circulating TGF-Beta and PD-L1 in Pancreatic Cancer | 1-gen-2022 | Garajová, Ingrid; Cavazzoni, Andrea; Verze, Michela; Minari, Roberta; Pedrazzi, Giuseppe; Balsano, Rita; Gelsomino, Fabio; DALLA VALLE, Raffaele; Digiacomo, Graziana; Giovannetti, Elisa; Leonardi, Francesco | |
| Overcoming Palbociclib Resistance by Combined Treatment with PI3K/AKT/mTOR Inhibitors in Mesothelioma Cells | 1-gen-2018 | Digiacomo, Graziana; Fumarola, Claudia; Cretella, Daniele; Alfieri, Roberta; LA MONICA, Silvia; Petronini, Pier Giorgio; Bonelli, Mara; Cavazzoni, Andrea | |
| PD-L1 level is up-regulated in NSCLC cells after pemetrexed treatment | 1-gen-2018 | Cavazzoni, A.; Digiacomo, G.; La Monica, S.; Alfieri, R.; Fiorentino, M.; Ardizzoni, A.; Petronini, Pg. | |
| PD-L1 OVEREXPRESSION INDUCES ANGIOGENIC CYTOKINE SECRETION AND ENDOTHELIAL CELL MIGRATION VIA STAT SIGNALLING. | 1-gen-2023 | Digiacomo, G.; Cavazzoni, A.; Volta, F.; Alfieri, R.; Petronini, P. G.; Tiseo, M. | |
| PD-L1 overexpression induces STAT signaling and promotes the secretion of pro-angiogenic cytokines in non-small cell lung cancer (NSCLC) | 1-gen-2024 | Cavazzoni, A.; Digiacomo, G.; Volta, F.; Alfieri, R.; Giovannetti, E.; Gnetti, L.; Bellini, L.; Galetti, M.; Fumarola, C.; Xu, G.; Bonelli, M.; La Monica, S.; Verze, M.; Leonetti, A.; Eltayeb, K.; D'Agnelli, S.; Moron Dalla Tor, L.; Minari, R.; Petronini, P. G.; Tiseo, M. | |
| Pemetrexed enhances membrane PD-L1 expression and potentiates T cell-mediated cytotoxicity by anti-PD-L1 antibody therapy in non-small-cell lung cancer | 1-gen-2020 | Cavazzoni, A.; Digiacomo, G.; Alfieri, R.; La Monica, S.; Fumarola, C.; Galetti, M.; Bonelli, M.; Cretella, D.; Barili, V.; Zecca, A.; Giovannetti, E.; Fiorentino, M.; Tiseo, M.; Petronini, P. G.; Ardizzoni, A. |