DIGIACOMO, GRAZIANA

DIGIACOMO, GRAZIANA  

Dipartimento di Medicina e Chirurgia  

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Titolo Data di pubblicazione Autore(i) File
Acquired BRAF G469A Mutation as a Resistance Mechanism to First-Line Osimertinib Treatment in NSCLC Cell Lines Harboring an EGFR Exon 19 Deletion 1-gen-2019 La Monica, S.; Minari, R.; Cretella, D.; Bonelli, M.; Fumarola, C.; Cavazzoni, A.; Galetti, M.; Digiacomo, G.; Riccardi, F.; Petronini, P. G.; Tiseo, M.; Alfieri, R.
The anti-tumor efficacy of CDK4/6 inhibition is enhanced by the combination with PI3K/AKT/mTOR inhibitors through impairment of glucose metabolism in TNBC cells 1-gen-2018 Cretella, Daniele; Ravelli, Andrea; Fumarola, Claudia; LA MONICA, Silvia; Digiacomo, Graziana; Cavazzoni, Andrea; Alfieri, Roberta; Biondi, Alessandra; Generali, Daniele; Bonelli, Mara; Petronini, Pier Giorgio
Balancing reactivity and antitumor activity: heteroarylthioacetamide derivatives as potent and time-dependent inhibitors of EGFR 1-gen-2019 Castelli, R; Bozza, N; Cavazzoni, A; Bonelli, M; Vacondio, F; Ferlenghi, F; Callegari, D; Silva, C; Rivara, S; Lodola, A; Digiacomo, G; Fumarola, C; Alfieri, R; Petronini, Pg; Mor, M.
Biological hallmarks and new therapeutic approaches for the treatment of pdac 1-gen-2021 Digiacomo, G.; Volta, F.; Garajova, I.; Balsano, R.; Cavazzoni, A.
CDK4/6 inhibitors improve the anti-tumor efficacy of lenvatinib in hepatocarcinoma cells 1-gen-2022 Digiacomo, Graziana; Fumarola, Claudia; La Monica, Silvia; Bonelli, Mara; Cavazzoni, Andrea; Galetti, Maricla; Terenziani, Rita; Eltayeb, Kamal; Volta, Francesco; Zoppi, Silvia; Bertolini, Patrizia; Missale, Gabriele; Alfieri, Roberta; Petronini, Pier Giorgio
Chromatin-associated CSF-1R binds to the promoter of proliferation-related genes in breast cancer cells 1-gen-2014 Barbetti, V.; Morandi, A.; Tusa, I.; Digiacomo, Graziana; Riverso, M.; Marzi, I.; Cipolleschi, M. G.; Bessi, S.; Giannini, A.; Di Leo, A.; Dello Sbarba, P.; Rovida, E.
Combined Inhibition of CDK4/6 and PI3K/AKT/mTOR Pathways Induces a Synergistic Anti-Tumor Effect in Malignant Pleural Mesothelioma Cells. 1-gen-2017 Bonelli, Mara; Digiacomo, Graziana; Fumarola, Claudia; Alfieri, Roberta; Quaini, Federico; Falco, Angela; Madeddu, Denise; LA MONICA, Silvia; Cretella, Daniele; Ravelli, Andrea; Ulivi, P; Tebaldi, M; Calistri, D; Delmonte, A; Ampollini, Luca; Carbognani, Paolo; Tiseo, Marcello; Cavazzoni, Andrea; Petronini, Pier Giorgio
Dual inhibition of CDK4/6 and PI3K/AKT/mTOR signaling impairs energy metabolism in MPM cancer cells 1-gen-2020 Bonelli, M.; Terenziani, R.; Zoppi, S.; Fumarola, C.; La Monica, S.; Cretella, D.; Alfieri, R.; Cavazzoni, A.; Digiacomo, G.; Galetti, M.; Petronini, P. G.
Efficacy of the cdk4/6 dual inhibitor abemaciclib in egfr-mutated nsclc cell lines with different resistance mechanisms to osimertinib 1-gen-2021 LA Monica, S.; Fumarola, C.; Cretella, D.; Bonelli, M.; Minari, R.; Cavazzoni, A.; Digiacomo, G.; Galetti, M.; Volta, F.; Mancini, M.; Petronini, P. G.; Tiseo, M.; Alfieri, R.
Enhanced efficacy of AKT and FAK kinase combined inhibition in squamous cell lung carcinomas with stable reduction in PTEN 1-gen-2017 Cavazzoni, Andrea; La Monica, Silvia; Alfieri, Roberta; Ravelli, Andrea; Steen, Nele Van Der; Sciarrillo, Rocco; Madeddu, Denise; Lagrasta, Costanza Anna Maria; Quaini, Federico; Bonelli, Mara; Fumarola, Claudia; Cretella, Daniele; Digiacomo, Graziana; Tiseo, Marcello; Peters, Godefridus J.; Ardizzoni, Andrea; Petronini, Pier Giorgio; and Elisa, Giovannetti
Enhancement of the anti-tumor activity of FGFR1 inhibition in squamous cell lung cancer by targeting downstream signaling involved in glucose metabolism. 1-gen-2017 Fumarola, Claudia; Cretella, Daniele; LA MONICA, Silvia; Bonelli, Mara; Alfieri, Roberta; Caffarra, Cristina; Quaini, Federico; Madeddu, Denise; Falco, Angela; Cavazzoni, Andrea; Digiacomo, Graziana; Mazzaschi, Giulia; Vivo, Valentina; Barocelli, Elisabetta; Tiseo, Marcello; Petronini, Pier Giorgio; Ardizzoni, Andrea
Fibronectin induces macrophage migration through a SFK-FAK/CSF-1R pathway 1-gen-2017 Digiacomo, Graziana; Tusa, Ignazia; Bacci, Marina; Cipolleschi, Maria Grazia; Dello Sbarba, Persio; Rovida, Elisabetta
INCREASED SOLUBLE AND MEMBRANE-BOUND PD-L1 EXPRESSION IN NSCLC CELL LINES TREATED WITH PEMETREXED 1-gen-2018 Cavazzoni, A.; Digiacomo, G.; Petronini, P. G.; Fiorentino, M.; Ardizzoni, A.; Alfieri, R.
It Takes Two to Tango: Potential Prognostic Impact of Circulating TGF-Beta and PD-L1 in Pancreatic Cancer 1-gen-2022 Garajová, Ingrid; Cavazzoni, Andrea; Verze, Michela; Minari, Roberta; Pedrazzi, Giuseppe; Balsano, Rita; Gelsomino, Fabio; DALLA VALLE, Raffaele; Digiacomo, Graziana; Giovannetti, Elisa; Leonardi, Francesco
Overcoming Palbociclib Resistance by Combined Treatment with PI3K/AKT/mTOR Inhibitors in Mesothelioma Cells 1-gen-2018 Digiacomo, Graziana; Fumarola, Claudia; Cretella, Daniele; Alfieri, Roberta; LA MONICA, Silvia; Petronini, Pier Giorgio; Bonelli, Mara; Cavazzoni, Andrea
PD-L1 level is up-regulated in NSCLC cells after pemetrexed treatment 1-gen-2018 Cavazzoni, A.; Digiacomo, G.; La Monica, S.; Alfieri, R.; Fiorentino, M.; Ardizzoni, A.; Petronini, Pg.
Pemetrexed enhances membrane PD-L1 expression and potentiates T cell-mediated cytotoxicity by anti-PD-L1 antibody therapy in non-small-cell lung cancer 1-gen-2020 Cavazzoni, A.; Digiacomo, G.; Alfieri, R.; La Monica, S.; Fumarola, C.; Galetti, M.; Bonelli, M.; Cretella, D.; Barili, V.; Zecca, A.; Giovannetti, E.; Fiorentino, M.; Tiseo, M.; Petronini, P. G.; Ardizzoni, A.
Pre-treatment with the CDK4/6 inhibitor palbociclib improves the efficacy of paclitaxel in TNBC cells 1-gen-2019 Cretella, D.; Fumarola, C.; Bonelli, M.; Alfieri, R.; La Monica, S.; Digiacomo, G.; Cavazzoni, A.; Galetti, M.; Generali, D.; Petronini, P. G.
Prostaglandin E2 transactivates the colony-stimulating factor-1 receptor and synergizes with Colony-stimulating factor-1 in the induction of macrophage migration via the mitogen-activated protein kinase ERK1/2 1-gen-2015 Digiacomo, Graziana; Ziche, Marina; Sbarba, Persio Dello; Donnini, Sandra; Rovida, Elisabetta
PTEN Alterations as a Potential Mechanism for Tumor Cell Escape from PD-1/PD-L1 Inhibition 1-gen-2019 Cretella, Daniele; Digiacomo, Graziana; Giovannetti, Elisa; Cavazzoni, Andrea