FRANKO, NINA
FRANKO, NINA
Dipartimento di Scienze degli Alimenti e del Farmaco
Combination of SAXS and protein painting discloses the three-dimensional organization of the bacterial cysteine synthase complex, a potential target for enhancers of antibiotic action
2019-01-01 Rosa, B.; Marchetti, M.; Paredi, G.; Amenitsch, H.; Franko, N.; Benoni, R.; Giabbai, B.; De Marino, M. G.; Mozzarelli, A.; Ronda, L.; Storici, P.; Campanini, B.; Bettati, S.
Cyclopropane-1,2-dicarboxylic acids as new tools for the biophysical investigation of O-acetylserine sulfhydrylases by fluorimetric methods and saturation transfer difference (STD) NMR
2016-01-01 Annunziato, Giannamaria; Pieroni, Marco; Benoni, Roberto; Campanini, Barbara; Pertinhez, Thelma; Pecchini, Chiara; Bruno, Agostino; Magalhães, Joana; Bettati, Stefano; Franko, Nina; Mozzarelli, Andrea; Costantino, Gabriele
Discovery of novel fragments inhibiting O-acetylserine sulphhydrylase by combining scaffold hopping and ligand–based drug design
2018-01-01 Magalhães, Joana; Franko, Nina; Annunziato, Giannamaria; Welch, Martin; Dolan, Stephen K.; Bruno, Agostino; Mozzarelli, Andrea; Armao, Stefano; Jirgensons, Aigars; Pieroni, Marco; Costantino, Gabriele; Campanini, Barbara
Discovery of Substituted (2-Aminooxazol-4-yl)Isoxazole-3-carboxylic Acids as Inhibitors of Bacterial Serine Acetyltransferase in the Quest for Novel Potential Antibacterial Adjuvants
2021-01-01 Magalhães, Joana; Franko, Nina; Raboni, Samanta; Annunziato, Giannamaria; Tammela, Päivi; Bruno, Agostino; Bettati, Stefano; Armao, Stefano; Spadini, Costanza; Cabassi, Clotilde Silvia; Mozzarelli, Andrea; Pieroni, Marco; Campanini, Barbara; Costantino, Gabriele
Inhibition of Nonessential Bacterial Targets: Discovery of a Novel Serine O-Acetyltransferase Inhibitor
2020-01-01 Magalhaes, J.; Franko, N.; Raboni, S.; Annunziato, G.; Tammela, P.; Bruno, A.; Bettati, S.; Mozzarelli, A.; Pieroni, M.; Campanini, B.; Costantino, G.
Inhibition of O-acetylserine sulfhydrylase by fluoroalanine derivatives
2018-01-01 Franko, N.; Grammatoglou, K.; Campanini, B.; Costantino, G.; Jirgensons, A.; Mozzarelli, A.
Inhibitors of O-Acetylserine Sulfhydrylase with a Cyclopropane-Carboxylic Acid Scaffold Are Effective Colistin Adjuvants in Gram Negative Bacteria
2022-01-01 Annunziato, Giannamaria; Spadini, Costanza; Marchetti, Marialaura; Franko, Nina; Pavone, Marialaura; Iannarelli, Mattia; Bruno, Agostino; Pieroni, Marco; Bettati, Stefano; Cabassi, Clotilde Silvia; Campanini, Barbara; Costantino, Gabriele
Integration of Enhanced Sampling Methods with Saturation Transfer Difference Experiments to Identify Protein Druggable Pockets
2018-01-01 Magalhães, Joana; Annunziato, Giannamaria; Franko, Nina; Pieroni, Marco; Campanini, Barbara; Bruno, Agostino; Costantino, Gabriele
Investigational Studies on a Hit Compound Cyclopropane-Carboxylic Acid Derivative Targeting O-Acetylserine Sulfhydrylase as a Colistin Adjuvant
2021-01-01 Annunziato, G.; Spadini, C.; Franko, N.; Storici, P.; Demitri, N.; Pieroni, M.; Flisi, S.; Rosati, L.; Iannarelli, M.; Marchetti, M.; Magalhaes, J.; Bettati, S.; Mozzarelli, A.; Cabassi, C. S.; Campanini, B.; Costantino, G.
Modulation of Escherichia coli serine acetyltransferase catalytic activity in the cysteine synthase complex
2017-01-01 Benoni, Roberto; DE BEI, Omar; Paredi, Gianluca; Hayes, Christopher S.; Franko, Nina; Mozzarelli, Andrea; Bettati, Stefano; Campanini, Barbara
Refining the structure−activity relationships of 2-phenylcyclopropane carboxylic acids as inhibitors of O-acetylserine sulfhydrylase isoforms
2019-01-01 Magalhães, Joana; Franko, Nina; Annunziato, Giannamaria; Pieroni, Marco; Benoni, Roberto; Nikitjuka, Anna; Mozzarelli, Andrea; Bettati, Stefano; Karawajczyk, Anna; Jirgensons, Aigars; Campanini, Barbara; Costantino, Gabriele
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Combination of SAXS and protein painting discloses the three-dimensional organization of the bacterial cysteine synthase complex, a potential target for enhancers of antibiotic action | 1-gen-2019 | Rosa, B.; Marchetti, M.; Paredi, G.; Amenitsch, H.; Franko, N.; Benoni, R.; Giabbai, B.; De Marino, M. G.; Mozzarelli, A.; Ronda, L.; Storici, P.; Campanini, B.; Bettati, S. | |
| Cyclopropane-1,2-dicarboxylic acids as new tools for the biophysical investigation of O-acetylserine sulfhydrylases by fluorimetric methods and saturation transfer difference (STD) NMR | 1-gen-2016 | Annunziato, Giannamaria; Pieroni, Marco; Benoni, Roberto; Campanini, Barbara; Pertinhez, Thelma; Pecchini, Chiara; Bruno, Agostino; Magalhães, Joana; Bettati, Stefano; Franko, Nina; Mozzarelli, Andrea; Costantino, Gabriele | |
| Discovery of novel fragments inhibiting O-acetylserine sulphhydrylase by combining scaffold hopping and ligand–based drug design | 1-gen-2018 | Magalhães, Joana; Franko, Nina; Annunziato, Giannamaria; Welch, Martin; Dolan, Stephen K.; Bruno, Agostino; Mozzarelli, Andrea; Armao, Stefano; Jirgensons, Aigars; Pieroni, Marco; Costantino, Gabriele; Campanini, Barbara | |
| Discovery of Substituted (2-Aminooxazol-4-yl)Isoxazole-3-carboxylic Acids as Inhibitors of Bacterial Serine Acetyltransferase in the Quest for Novel Potential Antibacterial Adjuvants | 1-gen-2021 | Magalhães, Joana; Franko, Nina; Raboni, Samanta; Annunziato, Giannamaria; Tammela, Päivi; Bruno, Agostino; Bettati, Stefano; Armao, Stefano; Spadini, Costanza; Cabassi, Clotilde Silvia; Mozzarelli, Andrea; Pieroni, Marco; Campanini, Barbara; Costantino, Gabriele | |
| Inhibition of Nonessential Bacterial Targets: Discovery of a Novel Serine O-Acetyltransferase Inhibitor | 1-gen-2020 | Magalhaes, J.; Franko, N.; Raboni, S.; Annunziato, G.; Tammela, P.; Bruno, A.; Bettati, S.; Mozzarelli, A.; Pieroni, M.; Campanini, B.; Costantino, G. | |
| Inhibition of O-acetylserine sulfhydrylase by fluoroalanine derivatives | 1-gen-2018 | Franko, N.; Grammatoglou, K.; Campanini, B.; Costantino, G.; Jirgensons, A.; Mozzarelli, A. | |
| Inhibitors of O-Acetylserine Sulfhydrylase with a Cyclopropane-Carboxylic Acid Scaffold Are Effective Colistin Adjuvants in Gram Negative Bacteria | 1-gen-2022 | Annunziato, Giannamaria; Spadini, Costanza; Marchetti, Marialaura; Franko, Nina; Pavone, Marialaura; Iannarelli, Mattia; Bruno, Agostino; Pieroni, Marco; Bettati, Stefano; Cabassi, Clotilde Silvia; Campanini, Barbara; Costantino, Gabriele | |
| Integration of Enhanced Sampling Methods with Saturation Transfer Difference Experiments to Identify Protein Druggable Pockets | 1-gen-2018 | Magalhães, Joana; Annunziato, Giannamaria; Franko, Nina; Pieroni, Marco; Campanini, Barbara; Bruno, Agostino; Costantino, Gabriele | |
| Investigational Studies on a Hit Compound Cyclopropane-Carboxylic Acid Derivative Targeting O-Acetylserine Sulfhydrylase as a Colistin Adjuvant | 1-gen-2021 | Annunziato, G.; Spadini, C.; Franko, N.; Storici, P.; Demitri, N.; Pieroni, M.; Flisi, S.; Rosati, L.; Iannarelli, M.; Marchetti, M.; Magalhaes, J.; Bettati, S.; Mozzarelli, A.; Cabassi, C. S.; Campanini, B.; Costantino, G. | |
| Modulation of Escherichia coli serine acetyltransferase catalytic activity in the cysteine synthase complex | 1-gen-2017 | Benoni, Roberto; DE BEI, Omar; Paredi, Gianluca; Hayes, Christopher S.; Franko, Nina; Mozzarelli, Andrea; Bettati, Stefano; Campanini, Barbara | |
| Refining the structure−activity relationships of 2-phenylcyclopropane carboxylic acids as inhibitors of O-acetylserine sulfhydrylase isoforms | 1-gen-2019 | Magalhães, Joana; Franko, Nina; Annunziato, Giannamaria; Pieroni, Marco; Benoni, Roberto; Nikitjuka, Anna; Mozzarelli, Andrea; Bettati, Stefano; Karawajczyk, Anna; Jirgensons, Aigars; Campanini, Barbara; Costantino, Gabriele |