Aim: This study evaluates the occurrence of Hepatitis E virus (HEV), Mammalian orthoreovirus (MRV), and Torque teno sus virus (TTSuV) in wild animals in Northern Italy to better estimate the risk of transmission to farmed animals and possibly to humans. Methods: Liver samples were collected from wild boars (n=405), wild ruminants (red deer, roe deer, and chamois; n=128), and hares (n=165) in areas with different characteristics: mountains (Alps and Prealps) with low farm density and anthropization; and flatland (Po Valley) with high farm density and anthropization. Detection and identification of the pathogens were performed by PCR and sequencing. Results: HEV detection was restricted to wild boars in the Po Valley (22.29% prevalence), while MRV was found in all studied species mainly in the mountains (up to 47.83%). MRV and TTSuV2 were found with high prevalence in hares living in both areas (49.09% and 37.58%, respectively). TTSuV1 was instead seldomly detected mainly in wild boars in the mountain areas (3.48%). Conclusions: Our findings shed light on the distribution of three swine-related viruses in wild fauna in Italy. Given the zoonotic potential of HEV, wild boar surveillance in areas with intensive pig farming would be advisable. The high prevalence of MRV and TTV in hares suggests their role as reservoir and potentially in viral amplification: their surveillance could be helpful to monitor viral diffusion and risk for farmed animals. The joint surveillance of domestic and wild animals could enhance the safety of farmed animals and protect human health in a One Health perspective. Funding: This research was funded by the Italian Ministry of Health, grant number RF-2016-02361926

Detection of three swine-related viruses (Hepatitis E Virus-HEV, Mammalian Orthoreovirus - MRV, and Torque Teno Sus Virus, TTSUV) in the wild fauna of Northern Italy / Arnaboldi, Sara; Righi, Francesco; Filipello, Virginia; Trogu, Tiziana; Lelli, Davide; Bianchi, Alessandro; Bonardi, Silvia; Pavoni, Enrico; Bertasi, Barbara; Lavazza, Antonio. - ELETTRONICO. - (2021), pp. P007.47-P007.47. (Intervento presentato al convegno 3rd Annual Scientific Meeting of the One Health EJ tenutosi a Copenhagen nel 9-11 June 2021).

Detection of three swine-related viruses (Hepatitis E Virus-HEV, Mammalian Orthoreovirus - MRV, and Torque Teno Sus Virus, TTSUV) in the wild fauna of Northern Italy

Silvia Bonardi;
2021-01-01

Abstract

Aim: This study evaluates the occurrence of Hepatitis E virus (HEV), Mammalian orthoreovirus (MRV), and Torque teno sus virus (TTSuV) in wild animals in Northern Italy to better estimate the risk of transmission to farmed animals and possibly to humans. Methods: Liver samples were collected from wild boars (n=405), wild ruminants (red deer, roe deer, and chamois; n=128), and hares (n=165) in areas with different characteristics: mountains (Alps and Prealps) with low farm density and anthropization; and flatland (Po Valley) with high farm density and anthropization. Detection and identification of the pathogens were performed by PCR and sequencing. Results: HEV detection was restricted to wild boars in the Po Valley (22.29% prevalence), while MRV was found in all studied species mainly in the mountains (up to 47.83%). MRV and TTSuV2 were found with high prevalence in hares living in both areas (49.09% and 37.58%, respectively). TTSuV1 was instead seldomly detected mainly in wild boars in the mountain areas (3.48%). Conclusions: Our findings shed light on the distribution of three swine-related viruses in wild fauna in Italy. Given the zoonotic potential of HEV, wild boar surveillance in areas with intensive pig farming would be advisable. The high prevalence of MRV and TTV in hares suggests their role as reservoir and potentially in viral amplification: their surveillance could be helpful to monitor viral diffusion and risk for farmed animals. The joint surveillance of domestic and wild animals could enhance the safety of farmed animals and protect human health in a One Health perspective. Funding: This research was funded by the Italian Ministry of Health, grant number RF-2016-02361926
2021
Detection of three swine-related viruses (Hepatitis E Virus-HEV, Mammalian Orthoreovirus - MRV, and Torque Teno Sus Virus, TTSUV) in the wild fauna of Northern Italy / Arnaboldi, Sara; Righi, Francesco; Filipello, Virginia; Trogu, Tiziana; Lelli, Davide; Bianchi, Alessandro; Bonardi, Silvia; Pavoni, Enrico; Bertasi, Barbara; Lavazza, Antonio. - ELETTRONICO. - (2021), pp. P007.47-P007.47. (Intervento presentato al convegno 3rd Annual Scientific Meeting of the One Health EJ tenutosi a Copenhagen nel 9-11 June 2021).
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11381/2893810
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