Genomic variation extends from single nucleotide variants to large chromosomal rearrangements, but the extent of structural variation in Homo sapiens is still unclear. Almarri et al. provide a worldwide catalogue of structural variants present in human populations. Most of the reported variation is novel, with some variants being inherited from Neanderthals and Denisovans. Drift and selection shaped the distribution of these variants with some suggested to have functional implications.
A Worldwide Map of Human Structural Variants / Montinaro, F.; Capelli, C.. - In: TRENDS IN GENETICS. - ISSN 0168-9525. - 36:10(2020), pp. 722-725. [10.1016/j.tig.2020.07.002]
A Worldwide Map of Human Structural Variants
Capelli C.
Conceptualization
2020-01-01
Abstract
Genomic variation extends from single nucleotide variants to large chromosomal rearrangements, but the extent of structural variation in Homo sapiens is still unclear. Almarri et al. provide a worldwide catalogue of structural variants present in human populations. Most of the reported variation is novel, with some variants being inherited from Neanderthals and Denisovans. Drift and selection shaped the distribution of these variants with some suggested to have functional implications.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
